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Association of the G473A Polymorphism and Expression of Lysyl Oxidase with Breast Cancer Risk and Survival in European Women: A Hospital-Based Case-Control Study

Figure 1

Age at breast cancer onset as a function of LOX G473A genotype.

(A) Boxplot of the age at onset of patients with the homozygous genotype GG and of A-carriers. p = 0.04, unpaired two-sided t-test. (B) Curves of the cumulative breast cancer incidence at the indicated age at onset of GG patients and of A-carriers. p = 0.01, log-rank test. A-carrier, patients with the GA (n = 93) or AA (n = 11) genotype.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0105579.g001