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Genome-Wide Screen of DNA Methylation Changes Induced by Low Dose X-Ray Radiation in Mice

Figure 1

Effects of low dose X-rays on global methylation levels in mouse blood.

Whole blood was sampled 2(dC and 5-mdC) detected by HPLC. Standard curve of dC(A) and 5mdC (B). DNA hydrolyzate compared with standard by liquid chromatography, early effects (C) and delay effects (D). Global methylation represented by 5-mdC(%), early effects (E) and delay effects (F). *P<0.05 versus control. P>0.05 versus control.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0090804.g001