Opposite Effect of Mast Cell Stabilizers Ketotifen and Tranilast on the Vasoconstrictor Response to Electrical Field Stimulation in Rat Mesenteric Artery
Figure 6
Effect of ketotifen or tranilast on nitrergic innervation function.
Effect of preincubation with 0.1 mmol/L L-NAME or 1 µmol/L 1400W on the frequency-response curves in control (A) ketotifen-incubated (B) or tranilast-incubated (C) mesenteric segments. Results (means + S.E.M.) are expressed as a percentage of tone induced by 75 mmol/L KCl. n = 6 animals each group.
