About the Authors

Alexey Fomenkov

Contributed equally to this work with: Alexey Fomenkov, Zhiyi Sun, Deborah K. Dila

Affiliation Research Department, New England Biolabs, Ipswich, MA, United States of America

Zhiyi Sun

Contributed equally to this work with: Alexey Fomenkov, Zhiyi Sun, Deborah K. Dila

Affiliation Research Department, New England Biolabs, Ipswich, MA, United States of America

Deborah K. Dila

Contributed equally to this work with: Alexey Fomenkov, Zhiyi Sun, Deborah K. Dila

Current address: University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America.

Affiliation Research Department, New England Biolabs, Ipswich, MA, United States of America

Brian P. Anton

Affiliation Research Department, New England Biolabs, Ipswich, MA, United States of America

Richard J. Roberts

Affiliation Research Department, New England Biolabs, Ipswich, MA, United States of America

Elisabeth A. Raleigh

raleigh@neb.com

Affiliation Research Department, New England Biolabs, Ipswich, MA, United States of America

Competing Interests

New England Biolabs provides DNA-active enzymes and sequencing kits commercially. The commercial role of NEB does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: EAR. Data curation: AF ZS BA. Formal analysis: ZS. Funding acquisition: EAR RJR. Investigation: DKD AF BA. Methodology: AF ZS EAR RJR. Resources: RJR. Software: ZS. Supervision: EAR. Visualization: ZS EAR RJR. Writing – original draft: AF ZS EAR. Writing – review & editing: EAR.