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Open Access
Peer-reviewed
Research Article
Screening uptake of colonoscopy versus fecal immunochemical testing in first-degree relatives of patients with non-syndromic colorectal cancer: A multicenter, open-label, parallel-group, randomized trial (ParCoFit study)
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Natalia González-López ,
Contributed equally to this work with: Natalia González-López, Enrique Quintero
Roles Data curation, Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
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Enrique Quintero ,
Contributed equally to this work with: Natalia González-López, Enrique Quintero
Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – original draft
* E-mail: equinter@ull.edu.es
Affiliations Department of Gastroenterology of Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, Instituto Universitario de Tecnologías Biomédicas (ITB) & Centro de Investigación Biomédica de Canarias (CIBICAN), Universidad de La Laguna, La Laguna, Tenerife, Spain
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Antonio Z. Gimeno-Garcia,
Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing
Affiliations Department of Gastroenterology of Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, Instituto Universitario de Tecnologías Biomédicas (ITB) & Centro de Investigación Biomédica de Canarias (CIBICAN), Universidad de La Laguna, La Laguna, Tenerife, Spain
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Luis Bujanda,
Roles Investigation, Supervision, Writing – review & editing
Affiliations Department of Gastroenterology of Hospital Universitario Donostia, Instituto Biodonostia, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Universidad del País Vasco (UPV/EHU), San Sebastián, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain, Department of Biochemistry and Genetics, School of Sciences, University of Navarra, Pamplona, Spain
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Jesús Banales,
Roles Investigation, Writing – review & editing
Affiliations Department of Gastroenterology of Hospital Universitario Donostia, Instituto Biodonostia, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Universidad del País Vasco (UPV/EHU), San Sebastián, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain, Department of Biochemistry and Genetics, School of Sciences, University of Navarra, Pamplona, Spain
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Joaquin Cubiella,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Department of Gastroenterology, Hospital Universitario de Ourense, Ourense, Spain
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María Salve-Bouzo,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology, Hospital Universitario de Ourense, Ourense, Spain
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Jesus Miguel Herrero-Rivas,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology, Hospital Universitario de Ourense, Ourense, Spain
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Estela Cid-Delgado,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology, Hospital Universitario de Ourense, Ourense, Spain
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Victoria Alvarez-Sanchez,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Complexo Hospitalario de Pontevedra, Pontevedra, Spain
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Alejandro Ledo-Rodríguez,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Complexo Hospitalario de Pontevedra, Pontevedra, Spain
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Maria Luisa de-Castro-Parga,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Complexo Hospitalario de Vigo, Vigo, Spain
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Romina Fernández-Poceiro,
Roles Investigation, Validation
Affiliation Department of Gastroenterology of Complexo Hospitalario de Vigo, Vigo, Spain
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Luciano Sanromán-Álvarez,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Complexo Hospitalario de Vigo, Vigo, Spain
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Jose Santiago-Garcia,
Roles Investigation, Writing – review & editing
Affiliation IDIPHISA, Department of Gastroenterology of Hospital Universitario Puerta de Hierro-Majadahonda o, Madrid, Spain
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Alberto Herreros-de-Tejada,
Roles Investigation, Supervision, Writing – review & editing
Affiliation IDIPHISA, Department of Gastroenterology of Hospital Universitario Puerta de Hierro-Majadahonda o, Madrid, Spain
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Teresa Ocaña-Bombardo,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology, Hospital Clínic Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer), University of Barcelona, Barcelona, Spain
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Francesc Balaguer,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Department of Gastroenterology, Hospital Clínic Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer), University of Barcelona, Barcelona, Spain
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María Rodríguez-Soler,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology, Instituto de Investigación Sanitaria ISABIAL, Hospital General Universitario Dr. Balmis, Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain
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Rodrigo Jover,
Roles Investigation, Validation, Writing – review & editing
Affiliation Department of Gastroenterology, Instituto de Investigación Sanitaria ISABIAL, Hospital General Universitario Dr. Balmis, Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain
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Marta Ponce,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario La Fe de Valencia, Valencia, Spain
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Cristina Alvarez-Urturi,
Roles Investigation, Writing – review & editing
Affiliation Gastroenterology Department, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain
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Xavier Bessa,
Roles Investigation, Writing – review & editing
Affiliation Gastroenterology Department, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain
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Maria-Pilar Roncales,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario Lozano Blesa de Zaragoza, IIS Aragón. CIBERehd, Zaragoza, Spain
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Federico Sopeña,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario Lozano Blesa de Zaragoza, IIS Aragón. CIBERehd, Zaragoza, Spain
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Angel Lanas,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario Lozano Blesa de Zaragoza, IIS Aragón. CIBERehd, Zaragoza, Spain
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David Nicolás-Pérez,
Roles Investigation, Software, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
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Zaida Adrián-de-Ganzo,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
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Marta Carrillo-Palau,
Roles Investigation, Writing – review & editing
Affiliation Department of Gastroenterology of Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
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Enrique González-Dávila,
Roles Formal analysis, Writing – review & editing
Affiliation Departamento de Matemáticas, Estadística e Investigación Operativa, Instituto IMAULL, Universidad de La Laguna, San Cristóbal de La Laguna, Spain
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- On behalf of the Oncology Group of Asociación Española de Gastroenterología
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Screening uptake of colonoscopy versus fecal immunochemical testing in first-degree relatives of patients with non-syndromic colorectal cancer: A multicenter, open-label, parallel-group, randomized trial (ParCoFit study)
- Natalia González-López,
- Enrique Quintero,
- Antonio Z. Gimeno-Garcia,
- Luis Bujanda,
- Jesús Banales,
- Joaquin Cubiella,
- María Salve-Bouzo,
- Jesus Miguel Herrero-Rivas,
- Estela Cid-Delgado,
- Victoria Alvarez-Sanchez
- Published: October 24, 2023
- https://doi.org/10.1371/journal.pmed.1004298