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Major histocompatibility complex  
PLOS Genetics  
Accurate detection of shared genetic architecture from GWAS summary statistics in the small-sample context

Thomas W. Willis, Chris Wallace

Methods | published 16 Aug 2023 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1010852

Views: 1666Citations: 4Saves: 0 • Shares: 0

Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

Arne Claeys, Tom Luijts, Kathleen Marchal, Jimmy Van den Eynden

Research Article | published 08 Feb 2021 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1009368

Views: 3783Citations: 23Saves: 28 • Shares: 4

The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries)

Alexandra M. Sparks, Kathryn Watt, Rona Sinclair, Jill G. Pilkington, Josephine M. Pemberton, Tom N. McNeilly, Daniel H. Nussey, Susan E. Johnston

Research Article | published 07 Nov 2019 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1008461

Views: 5764Citations: 30Saves: 50 • Shares: 1

Quantifying immune-based counterselection of somatic mutations

Fan Yang, Dae-Kyum Kim, Hidewaki Nakagawa, Shuto Hayashi, Seiya Imoto, Lincoln Stein, Frederick P. Roth

Research Article | published 25 Jul 2019 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1008227

Views: 8249Citations: 15Saves: 38 • Shares: 2

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians

Julio E. Molineros, Loren L. Looger, Kwangwoo Kim, Yukinori Okada, Chikashi Terao, Celi Sun, Xu-jie Zhou, Prithvi Raj, Yuta Kochi, Akari Suzuki, Shuji Akizuki, Shuichiro Nakabo, So-Young Bang, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Yong-Beom Park, Jung-Yoon Choe, Seung-Cheol Shim, Shin-Seok Lee, Xiaoxia Zuo, Kazuhiko Yamamoto, Quan-Zhen Li, Nan Shen, Lauren L. Porter, John B. Harley, Kek Heng Chua, Hong Zhang, Edward K. Wakeland, Betty P. Tsao, Sang-Cheol Bae, Swapan K. Nath

Research Article | published 25 Apr 2019 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1008092

Views: 5540Citations: 45Saves: 47 • Shares: 0

Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry

Calvin Chi, Xiaorong Shao, Brooke Rhead, Edlin Gonzales, Jessica B. Smith, Anny H. Xiang, Jennifer Graves, Amy Waldman, Timothy Lotze, Teri Schreiner, Bianca Weinstock-Guttman, Gregory Aaen, Jan-Mendelt Tillema, Jayne Ness, Meghan Candee, Lauren Krupp, Mark Gorman, Leslie Benson, Tanuja Chitnis, Soe Mar, Anita Belman, Theron Charles Casper, John Rose, Manikum Moodley, Mary Rensel, Moses Rodriguez, Benjamin Greenberg, Llana Kahn, Jennifer Rubin, Catherine Schaefer, Emmanuelle Waubant, Annette Langer-Gould, Lisa F. Barcellos

Research Article | published 17 Jan 2019 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1007808

Views: 6753Citations: 57Saves: 82 • Shares: 3

Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania

Matt Ravenhall, Susana Campino, Nuno Sepúlveda, Alphaxard Manjurano, Behzad Nadjm, George Mtove, Hannah Wangai, Caroline Maxwell, Raimos Olomi, Hugh Reyburn, Christopher J. Drakeley, Eleanor M. Riley, Taane G. Clark, in collaboration with MalariaGEN

Research Article | published 30 Jan 2018 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1007172

Views: 6184Citations: 62Saves: 152 • Shares: 6

Identification of an elaborate NK-specific system regulating HLA-C expression

Hongchuan Li, Martin A. Ivarsson, Victoria E. Walker-Sperling, Jeff Subleski, Jenna K. Johnson, Paul W. Wright, Mary Carrington, Niklas K. Björkström, Daniel W. McVicar, Stephen K. Anderson

Research Article | published 12 Jan 2018 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1007163

Views: 5442Citations: 25Saves: 44 • Shares: 13

Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study

Paul J. Leo, Margaret M. Madeleine, Sophia Wang, Stephen M. Schwartz, Felicity Newell, Ulrika Pettersson-Kymmer, Kari Hemminki, Goran Hallmans, Sven Tiews, Winfried Steinberg, Janet S. Rader, Felipe Castro, Mahboobeh Safaeian, Eduardo L. Franco, François Coutlée, Claes Ohlsson, Adrian Cortes, Mhairi Marshall, Pamela Mukhopadhyay, Katie Cremin, Lisa G. Johnson, Suzanne Garland, Sepehr N. Tabrizi, Nicolas Wentzensen, Freddy Sitas, Julian Little, Maggie Cruickshank, Ian H. Frazer, Allan Hildesheim, Matthew A. Brown

Research Article | published 14 Aug 2017 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1006866

Views: 7847Citations: 98Saves: 117 • Shares: 8

Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation

Arne W. Mould, Marc A. J. Morgan, Andrew C. Nelson, Elizabeth K. Bikoff, Elizabeth J. Robertson

Research Article | published 09 Jul 2015 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1005375

Views: 6270Citations: 34Saves: 53 • Shares: 2

NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module

Kristina Ludigs, Queralt Seguín-Estévez, Sylvain Lemeille, Isabel Ferrero, Giorgia Rota, Sonia Chelbi, Chantal Mattmann, H. Robson MacDonald, Walter Reith, Greta Guarda

Research Article | published 26 Mar 2015 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1005088

Views: 6675Citations: 86Saves: 0 • Shares: 0

Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX

Charles E. Larsen, Dennis R. Alford, Michael R. Trautwein, Yanoh K. Jalloh, Jennifer L. Tarnacki, Sushruta K. Kunnenkeri, Dolores A. Fici, Edmond J. Yunis, Zuheir L. Awdeh, Chester A. Alper

Research Article | published 09 Oct 2014 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1004637

Views: 4233Citations: 16Saves: 24 • Shares: 1

Introgression from Domestic Goat Generated Variation at the Major Histocompatibility Complex of Alpine Ibex

Christine Grossen, Lukas Keller, Iris Biebach, The International Goat Genome Consortium , Daniel Croll

Research Article | published 19 Jun 2014 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1004438

Views: 8447Citations: 100Saves: 134 • Shares: 5

An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection

Diego Forni, Rachele Cagliani, Claudia Tresoldi, Uberto Pozzoli, Luca De Gioia, Giulia Filippi, Stefania Riva, Giorgia Menozzi, Marta Colleoni, Mara Biasin, Sergio Lo Caputo, Francesco Mazzotta, Giacomo P. Comi, Nereo Bresolin, Mario Clerici, Manuela Sironi

Research Article | published 27 Mar 2014 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1004189

Views: 8693Citations: 37Saves: 72 • Shares: 7

Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat

Jonatan Tuncel, Sabrina Haag, Anthony C. Y. Yau, Ulrika Norin, Amelie Baud, Erik Lönnblom, Klio Maratou, A. Jimmy Ytterberg, Diana Ekman, Soley Thordardottir, Martina Johannesson, Alan Gillett, EURATRANS Consortium , Pernilla Stridh, Maja Jagodic, Tomas Olsson, Alberto Fernández-Teruel, Roman A. Zubarev, Richard Mott, Timothy J. Aitman, Jonathan Flint, Rikard Holmdahl

Research Article | published 20 Feb 2014 PLOS Genetics

https://doi.org/10.1371/journal.pgen.1004151

Views: 5293Citations: 15Saves: 24 • Shares: 2

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