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Accurate detection of shared genetic architecture from GWAS summary statistics in the small-sample context
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Thomas W. Willis, Chris Wallace
Methods |
published 16 Aug 2023
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1010852
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Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals
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Arne Claeys, Tom Luijts, Kathleen Marchal, Jimmy Van den Eynden
Research Article |
published 08 Feb 2021
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1009368
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The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries)
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Alexandra M. Sparks, Kathryn Watt, Rona Sinclair, Jill G. Pilkington, Josephine M. Pemberton, Tom N. McNeilly, Daniel H. Nussey, Susan E. Johnston
Research Article |
published 07 Nov 2019
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1008461
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Quantifying immune-based counterselection of somatic mutations
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Fan Yang, Dae-Kyum Kim, Hidewaki Nakagawa, Shuto Hayashi, Seiya Imoto, Lincoln Stein, Frederick P. Roth
Research Article |
published 25 Jul 2019
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1008227
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Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians
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Julio E. Molineros, Loren L. Looger, Kwangwoo Kim, Yukinori Okada, Chikashi Terao, Celi Sun, Xu-jie Zhou, Prithvi Raj, Yuta Kochi, Akari Suzuki, Shuji Akizuki, Shuichiro Nakabo, So-Young Bang, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Yong-Beom Park, Jung-Yoon Choe, Seung-Cheol Shim, Shin-Seok Lee, Xiaoxia Zuo, Kazuhiko Yamamoto, Quan-Zhen Li, Nan Shen, Lauren L. Porter, John B. Harley, Kek Heng Chua, Hong Zhang, Edward K. Wakeland, Betty P. Tsao, Sang-Cheol Bae, Swapan K. Nath
Research Article |
published 25 Apr 2019
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1008092
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Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry
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Calvin Chi, Xiaorong Shao, Brooke Rhead, Edlin Gonzales, Jessica B. Smith, Anny H. Xiang, Jennifer Graves, Amy Waldman, Timothy Lotze, Teri Schreiner, Bianca Weinstock-Guttman, Gregory Aaen, Jan-Mendelt Tillema, Jayne Ness, Meghan Candee, Lauren Krupp, Mark Gorman, Leslie Benson, Tanuja Chitnis, Soe Mar, Anita Belman, Theron Charles Casper, John Rose, Manikum Moodley, Mary Rensel, Moses Rodriguez, Benjamin Greenberg, Llana Kahn, Jennifer Rubin, Catherine Schaefer, Emmanuelle Waubant, Annette Langer-Gould, Lisa F. Barcellos
Research Article |
published 17 Jan 2019
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1007808
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Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania
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Matt Ravenhall, Susana Campino, Nuno Sepúlveda, Alphaxard Manjurano, Behzad Nadjm, George Mtove, Hannah Wangai, Caroline Maxwell, Raimos Olomi, Hugh Reyburn, Christopher J. Drakeley, Eleanor M. Riley, Taane G. Clark, in collaboration with MalariaGEN
Research Article |
published 30 Jan 2018
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1007172
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Identification of an elaborate NK-specific system regulating HLA-C expression
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Hongchuan Li, Martin A. Ivarsson, Victoria E. Walker-Sperling, Jeff Subleski, Jenna K. Johnson, Paul W. Wright, Mary Carrington, Niklas K. Björkström, Daniel W. McVicar, Stephen K. Anderson
Research Article |
published 12 Jan 2018
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1007163
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Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study
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Paul J. Leo, Margaret M. Madeleine, Sophia Wang, Stephen M. Schwartz, Felicity Newell, Ulrika Pettersson-Kymmer, Kari Hemminki, Goran Hallmans, Sven Tiews, Winfried Steinberg, Janet S. Rader, Felipe Castro, Mahboobeh Safaeian, Eduardo L. Franco, François Coutlée, Claes Ohlsson, Adrian Cortes, Mhairi Marshall, Pamela Mukhopadhyay, Katie Cremin, Lisa G. Johnson, Suzanne Garland, Sepehr N. Tabrizi, Nicolas Wentzensen, Freddy Sitas, Julian Little, Maggie Cruickshank, Ian H. Frazer, Allan Hildesheim, Matthew A. Brown
Research Article |
published 14 Aug 2017
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1006866
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Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation
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Arne W. Mould, Marc A. J. Morgan, Andrew C. Nelson, Elizabeth K. Bikoff, Elizabeth J. Robertson
Research Article |
published 09 Jul 2015
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1005375
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NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module
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Kristina Ludigs, Queralt Seguín-Estévez, Sylvain Lemeille, Isabel Ferrero, Giorgia Rota, Sonia Chelbi, Chantal Mattmann, H. Robson MacDonald, Walter Reith, Greta Guarda
Research Article |
published 26 Mar 2015
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1005088
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Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX
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Charles E. Larsen, Dennis R. Alford, Michael R. Trautwein, Yanoh K. Jalloh, Jennifer L. Tarnacki, Sushruta K. Kunnenkeri, Dolores A. Fici, Edmond J. Yunis, Zuheir L. Awdeh, Chester A. Alper
Research Article |
published 09 Oct 2014
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1004637
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Introgression from Domestic Goat Generated Variation at the Major Histocompatibility Complex of Alpine Ibex
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Christine Grossen, Lukas Keller, Iris Biebach, The International Goat Genome Consortium , Daniel Croll
Research Article |
published 19 Jun 2014
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1004438
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An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection
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Diego Forni, Rachele Cagliani, Claudia Tresoldi, Uberto Pozzoli, Luca De Gioia, Giulia Filippi, Stefania Riva, Giorgia Menozzi, Marta Colleoni, Mara Biasin, Sergio Lo Caputo, Francesco Mazzotta, Giacomo P. Comi, Nereo Bresolin, Mario Clerici, Manuela Sironi
Research Article |
published 27 Mar 2014
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1004189
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Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat
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Jonatan Tuncel, Sabrina Haag, Anthony C. Y. Yau, Ulrika Norin, Amelie Baud, Erik Lönnblom, Klio Maratou, A. Jimmy Ytterberg, Diana Ekman, Soley Thordardottir, Martina Johannesson, Alan Gillett, EURATRANS Consortium , Pernilla Stridh, Maja Jagodic, Tomas Olsson, Alberto Fernández-Teruel, Roman A. Zubarev, Richard Mott, Timothy J. Aitman, Jonathan Flint, Rikard Holmdahl
Research Article |
published 20 Feb 2014
PLOS Genetics
https://doi.org/10.1371/journal.pgen.1004151