- Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity
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Research Article | published 12 Dec 2024 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1011486
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- MAD1 upregulation sensitizes to inflammation-mediated tumor formation
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Research Article | published 07 Oct 2024 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1011437
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- Epithelial-specific ERBB3 deletion results in a genetic background-dependent increase in intestinal and colon polyps that is mediated by EGFR
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Research Article | published 29 Nov 2021 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1009931
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- Male-biased aganglionic megacolon in the TashT mouse model of Hirschsprung disease involves upregulation of p53 protein activity and Ddx3y gene expression
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Research Article | published 08 Sep 2020 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1009008
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- Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies
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Research Article | published 20 Apr 2020 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1008734
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- Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy
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Research Article | published 06 May 2019 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1007687
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- Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death
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Research Article | published 27 Sep 2018 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1007697
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- The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer
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Research Article | published 06 Sep 2018 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1007611
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- hnRNP I regulates neonatal immune adaptation and prevents colitis and colorectal cancer
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Research Article | published 15 Mar 2017 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1006672
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- Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility
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Research Article | published 22 Feb 2016 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1005880
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- Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium
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Research Article | published 03 Nov 2015 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1005638
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- EP4 Receptor–Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis
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Research Article | published 06 Oct 2015 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1005542
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- Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10
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Research Article | published 18 Mar 2015 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1005093
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- Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing
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Research Article | published 18 Sep 2014 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1004620
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- Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo
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Research Article | published 05 Jun 2014 PLOS Genetics
https://doi.org/10.1371/journal.pgen.1004299
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