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High-Resolution Mapping Reveals Links of HP1 with Active and Inactive Chromatin Components

Figure 2

Most HP1-Bound Genes Are Actively Transcribed

Density plot (smoothed histogram) showing the distribution of normalized expression levels of (A) nonpericentric and (B) pericentric genes that are strongly bound by HP1 (high HP1, average HP1 log2-ratio along entire gene >2 [red]) or genes with low or no binding by HP1 (low HP1, average HP1 log2-ratio along entire gene <2 [black]). Expression data were taken from Pickersgill et al. [50].

Figure 2

doi: https://doi.org/10.1371/journal.pgen.0030038.g002