Search Results | PLOS Computational Biology

Design of field trials for the evaluation of transmissible vaccines in animal populations

Justin K. Sheen, Lee Kennedy-Shaffer, Michael Z. Levy, Charlotte Jessica E. Metcalf

Research Article | published 03 Feb 2025 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012779

Views: 471 • Citations: 0 • Saves: 0 • Shares: 0

Predicting the infecting dengue serotype from antibody titre data using machine learning

Bethan Cracknell Daniels, Darunee Buddhari, Taweewun Hunsawong, Sopon Iamsirithaworn, Aaron R. Farmer, Derek A. T. Cummings, Kathryn B. Anderson, Ilaria Dorigatti

Research Article | published 23 Dec 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012188

Views: 705 • Citations: 0 • Saves: 15 • Shares: 1

GeM-LR: Discovering predictive biomarkers for small datasets in vaccine studies

Lin Lin, Rachel L. Spreng, Kelly E. Seaton, S. Moses Dennison, Lindsay C. Dahora, Daniel J. Schuster, Sheetal Sawant, Peter B. Gilbert, Youyi Fong, Neville Kisalu, Andrew J. Pollard, Georgia D. Tomaras, Jia Li

Research Article | published 14 Nov 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012581

Views: 675 • Citations: 0 • Saves: 0 • Shares: 0

Prioritising older individuals for COVID-19 booster vaccination leads to optimal public health outcomes in a range of socio-economic settings

Ioana Bouros, Edward M. Hill, Matt J. Keeling, Sam Moore, Robin N. Thompson

Research Article | published 08 Aug 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012309

Views: 1307 • Citations: 1 • Saves: 3 • Shares: 5

Impact of waning immunity against SARS-CoV-2 severity exacerbated by vaccine hesitancy

Chadi M. Saad-Roy, Sinead E. Morris, Mike Boots, Rachel E. Baker, Bryan L. Lewis, Jeremy Farrar, Madhav V. Marathe, Andrea L. Graham, Simon A. Levin, Caroline E. Wagner, C. Jessica E. Metcalf, Bryan T. Grenfell

Research Article | published 05 Aug 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012211

Views: 1513 • Citations: 3 • Saves: 3 • Shares: 33

When should lockdown be implemented? Devising cost-effective strategies for managing epidemics amid vaccine uncertainty

Nathan J. Doyle, Fergus Cumming, Robin N. Thompson, Michael J. Tildesley

Research Article | published 18 Jul 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012010

Views: 900 • Citations: 0 • Saves: 0 • Shares: 0

Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine

Wencel Valega-Mackenzie, Marisabel Rodriguez Messan, Osman N. Yogurtcu, Ujwani Nukala, Zuben E. Sauna, Hong Yang

Research Article | published 01 Mar 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011247

Views: 1497 • Citations: 2 • Saves: 5 • Shares: 2

Wildlife vaccination strategies for eliminating bovine tuberculosis in white-tailed deer populations

Aakash Pandey, Abigail B. Feuka, Melinda Cosgrove, Megan Moriarty, Anthony Duffiney, Kurt C. VerCauteren, Henry Campa III, Kim M. Pepin

Research Article | published 04 Jan 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011287

Views: 2054 • Citations: 3 • Saves: 12 • Shares: 1

Optimizing COVID-19 testing strategies on college campuses: Evaluation of the health and economic costs

Kaitlyn E. Johnson, Remy Pasco, Spencer Woody, Michael Lachmann, Maureen Johnson-Leon, Darlene Bhavnani, Jessica Klima, A. David Paltiel, Spencer J. Fox, Lauren Ancel Meyers

Research Article | published 22 Dec 2023 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011715

Views: 1027 • Citations: 3 • Saves: 11 • Shares: 3

Quantitative mechanistic model reveals key determinants of placental IgG transfer and informs prenatal immunization strategies