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Copy number variants underlie major selective sweeps in insecticide resistance genes in Anopheles arabiensis
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Eric R. Lucas, Sanjay C. Nagi, Bilali Kabula, Bernard Batengana, William Kisinza, Alexander Egyir-Yawson, John Essandoh, Sam Dadzie, Joseph Chabi, Arjen E. Van’t Hof, Emily J. Rippon, Dimitra Pipini, Nicholas J. Harding, Naomi A. Dyer, Chris S. Clarkson, Alistair Miles, David Weetman, Martin J. Donnelly
Short Reports |
published 05 Dec 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002898
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Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale
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Nhung Hoang, Neda Sardaripour, Grace D. Ramey, Kurt Schilling, Emily Liao, Yiting Chen, Jee Hyun Park, Xavier Bledsoe, Bennett A. Landman, Eric R. Gamazon, Mary Lauren Benton, John A. Capra, Mikail Rubinov
Methods and Resources |
published 13 Sep 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002782
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The genetic basis of the kākāpō structural color polymorphism suggests balancing selection by an extinct apex predator
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Lara Urban, Anna W. Santure, Lydia Uddstrom, Andrew Digby, Deidre Vercoe, Daryl Eason, Jodie Crane, Kākāpō Recovery Team , Matthew J. Wylie, Tāne Davis, Marissa F. LeLec, Joseph Guhlin, Simon Poulton, Jon Slate, Alana Alexander, Patricia Fuentes-Cross, Peter K. Dearden, Neil J. Gemmell, Farhan Azeem, Marvin Weyland, Harald G. L. Schwefel, Cock van Oosterhout, Hernán E. Morales
Short Reports |
published 10 Sep 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002755
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Multicellular magnetotactic bacteria are genetically heterogeneous consortia with metabolically differentiated cells
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George A. Schaible, Zackary J. Jay, John Cliff, Frederik Schulz, Colin Gauvin, Danielle Goudeau, Rex R. Malmstrom, S. Emil Ruff, Virginia Edgcomb, Roland Hatzenpichler
Research Article |
published 11 Jul 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002638
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Engineering of a high-fidelity Cas12a nuclease variant capable of allele-specific editing
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Jingjing Wei, Jingtong Liu, Ziwen Wang, Yuan Yang, Yuwen Tian, Shengzhou Wang, Bao-Qing Gao, Song Gao, Li Yang, Junnan Tang, Yongming Wang
Research Article |
published 12 Jun 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002680
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A few genetic variants go a long way in differentiating Penstemon species
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Yaniv Brandvain, Shelley Sianta
Primer |
published 29 Sep 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002322
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A few essential genetic loci distinguish Penstemon species with flowers adapted to pollination by bees or hummingbirds
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Carolyn A. Wessinger, Amanda M. Katzer, Paul M. Hime, Mark D. Rausher, John K. Kelly, Lena C. Hileman
Short Reports |
published 28 Sep 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002294
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Mitonuclear interactions shape both direct and parental effects of diet on fitness and involve a SNP in mitoribosomal 16s rRNA
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Adam J. Dobson, Susanne Voigt, Luisa Kumpitsch, Lucas Langer, Emmely Voigt, Rita Ibrahim, Damian K. Dowling, Klaus Reinhardt
Short Reports |
published 21 Aug 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002218
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Divergent combinations of cis-regulatory elements control the evolution of phenotypic plasticity
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Mohannad Dardiry, Gabi Eberhard, Hanh Witte, Christian Rödelsperger, James W. Lightfoot, Ralf J. Sommer
Short Reports |
published 17 Aug 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002270
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Pan-European study of genotypes and phenotypes in the Arabidopsis relative Cardamine hirsuta reveals how adaptation, demography, and development shape diversity patterns
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Lukas Baumgarten, Bjorn Pieper, Baoxing Song, Sébastien Mane, Janne Lempe, Jonathan Lamb, Elizabeth L. Cooke, Rachita Srivastava, Stefan Strütt, Danijela Žanko, Pedro GP Casimiro, Asis Hallab, Maria Cartolano, Alexander D. Tattersall, Bruno Huettel, Dmitry A. Filatov, Pavlos Pavlidis, Barbara Neuffer, Christos Bazakos, Hanno Schaefer, Richard Mott, Xiangchao Gan, Carlos Alonso-Blanco, Stefan Laurent, Miltos Tsiantis
Research Article |
published 18 Jul 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002191
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Tools for using the International Rice Genebank to breed for climate-resilient varieties
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Kenneth L. McNally, Amelia Henry
Community Page |
published 06 Jul 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002215
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Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome
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Brian V. Tsu, Rimjhim Agarwal, Nandan S. Gokhale, Jessie Kulsuptrakul, Andrew P. Ryan, Elizabeth J. Fay, Lennice K. Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A. Turcotte, Sofia E. Delgado-Rodriguez, Russell E. Vance, Jennifer L. Hyde, Ram Savan, Patrick S. Mitchell, Matthew D. Daugherty
Research Article |
published 08 Jun 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002144
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An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis
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Chengliang Wang, Jianbin Ruan
Primer |
published 04 May 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002103
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Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis
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Xinli Wang, Xuxia Wei, Yan Lu, Qinghuan Wang, Rong Fu, Yin Wang, Qin Wang, Xiangyan Wang, Shangwu Chen, Anlong Xu, Shaochun Yuan
Research Article |
published 03 May 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002062
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Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics
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Madeline G. Dans, Henni Piirainen, William Nguyen, Sachin Khurana, Somya Mehra, Zahra Razook, Niall D. Geoghegan, Aurelie T. Dawson, Sujaan Das, Molly Parkyn Schneider, Thorey K. Jonsdottir, Mikha Gabriela, Maria R. Gancheva, Christopher J. Tonkin, Vanessa Mollard, Christopher Dean Goodman, Geoffrey I. McFadden, Danny W. Wilson, Kelly L. Rogers, Alyssa E. Barry, Brendan S. Crabb, Tania F. de Koning-Ward, Brad E. Sleebs, Inari Kursula, Paul R. Gilson
Research Article |
published 13 Apr 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002066