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Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis
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Sarah Wettstadt, Francisco J. Marcos-Torres, Joaquín R. Otero-Asman, Alicia García-Puente, Álvaro Ortega, María A. Llamas
Short Reports |
published 02 Dec 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002920
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Structure of G protein-coupled receptor GPR1 bound to full-length chemerin adipokine reveals a chemokine-like reverse binding mode
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Aijun Liu, Yezhou Liu, Geng Chen, Wenping Lyu, Fang Ye, Junlin Wang, Qiwen Liao, Lizhe Zhu, Yang Du, Richard D. Ye
Research Article |
published 28 Oct 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002838
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Structure of the Nmd4-Upf1 complex supports conservation of the nonsense-mediated mRNA decay pathway between yeast and humans
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Irène Barbarin-Bocahu, Nathalie Ulryck, Amandine Rigobert, Nadia Ruiz Gutierrez, Laurence Decourty, Mouna Raji, Bhumika Garkhal, Hervé Le Hir, Cosmin Saveanu, Marc Graille
Short Reports |
published 27 Sep 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002821
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Alveolin proteins in the Toxoplasma inner membrane complex form a highly interconnected structure that maintains parasite shape and replication
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Peter S. Back, Vignesh Senthilkumar, Charles P. Choi, Justin J. Quan, Qing Lou, Anne K. Snyder, Andrew M. Ly, Justin G. Lau, Z. Hong Zhou, Gary E. Ward, Peter J. Bradley
Research Article |
published 12 Sep 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002809
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The conformational plasticity of structurally unrelated lipid transport proteins correlates with their mode of action
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Sriraksha Srinivasan, Andrea Di Luca, Daniel Álvarez, Arun T. John Peter, Charlotte Gehin, Museer A. Lone, Thorsten Hornemann, Giovanni D’Angelo, Stefano Vanni
Research Article |
published 19 Aug 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002737
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Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
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Kaleeckal G. Harikumar, Peishen Zhao, Brian P. Cary, Xiaomeng Xu, Aditya J. Desai, Maoqing Dong, Jesse I. Mobbs, Chirine Toufaily, Sebastian G. B. Furness, Arthur Christopoulos, Matthew J. Belousoff, Denise Wootten, Patrick M. Sexton, Laurence J. Miller
Update Article |
published 31 Jul 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002673
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FURNA: A database for functional annotations of RNA structures
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Chengxin Zhang, Lydia Freddolino
Methods and Resources |
published 29 Jul 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002476
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Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication
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Carlos A. Rodríguez-Salazar, Sarah van Tol, Olivier Mailhot, Maria Gonzalez-Orozco, Gabriel T. Galdino, Abbey N. Warren, Natalia Teruel, Padmanava Behera, Kazi Sabrina Afreen, Lihong Zhang, Terry L. Juelich, Jennifer K. Smith, María Inés Zylber, Alexander N. Freiberg, Rafael J. Najmanovich, Maria I. Giraldo, Ricardo Rajsbaum
Research Article |
published 29 Feb 2024
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002544
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SMOC-1 interacts with both BMP and glypican to regulate BMP signaling in C. elegans
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Melisa S. DeGroot, Byron Williams, Timothy Y. Chang, Maria L. Maas Gamboa, Isabel M. Larus, Garam Hong, J. Christopher Fromme, Jun Liu
Research Article |
published 17 Aug 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002272
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AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
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Hallvard Lauritz Olsvik, Terje Johansen
Primer |
published 08 Feb 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3002002
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AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs
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Tarhan Ibrahim, Virendrasinh Khandare, Federico Gabriel Mirkin, Yasin Tumtas, Doryen Bubeck, Tolga O. Bozkurt
Methods and Resources |
published 08 Feb 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3001962
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LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein
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Jarrod Shilts, Thomas W. M. Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J. D. Greenwood, Samuel James Watson, Brian M. Ortmann, Christian M. Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A. Nathan, Stefan Pöhlmann, Nicholas J. Matheson, Paul J. Lehner, Gavin J. Wright
Short Reports |
published 03 Feb 2023
PLOS Biology
https://doi.org/10.1371/journal.pbio.3001959
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Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications
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Nitika, Bo Zheng, Linhao Ruan, Jake T. Kline, Siddhi Omkar, Jacek Sikora, Mara Texeira Torres, Yuhao Wang, Jade E. Takakuwa, Romain Huguet, Cinzia Klemm, Verónica A. Segarra, Matthew J. Winters, Peter M. Pryciak, Peter H. Thorpe, Kazuo Tatebayashi, Rong Li, Luca Fornelli, Andrew W. Truman
Methods and Resources |
published 21 Oct 2022
PLOS Biology
https://doi.org/10.1371/journal.pbio.3001839
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The synaptic scaffold protein MPP2 interacts with GABAA receptors at the periphery of the postsynaptic density of glutamatergic synapses
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Bettina Schmerl, Niclas Gimber, Benno Kuropka, Alexander Stumpf, Jakob Rentsch, Stella-Amrei Kunde, Judith von Sivers, Helge Ewers, Dietmar Schmitz, Christian Freund, Jan Schmoranzer, Nils Rademacher, Sarah A. Shoichet
Research Article |
published 21 Mar 2022
PLOS Biology
https://doi.org/10.1371/journal.pbio.3001503
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Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation
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Dasol Han, Andrew P. Longhini, Xuemei Zhang, Vivian Hoang, Maxwell Z. Wilson, Kenneth S. Kosik
Short Reports |
published 10 Feb 2022
PLOS Biology
https://doi.org/10.1371/journal.pbio.3001535