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The cholesterol 24-hydroxylase CYP46A1 promotes α-synuclein pathology in Parkinson’s disease

Lijun Dai, Jiannan Wang, Lanxia Meng, Xingyu Zhang, Tingting Xiao, Min Deng, Guiqin Chen, Jing Xiong, Wei Ke, Zhengyuan Hong, Lihong Bu, Zhentao Zhang

Research Article | published 18 Feb 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002974

Views: 1818 • Citations: 0 • Saves: 5 • Shares: 13

SLMO transfers phosphatidylserine between the outer and inner mitochondrial membrane in Drosophila

Siwen Zhao, Xuguang Jiang, Ning Li, Tao Wang

Research Article | published 16 Dec 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002941

Views: 1224 • Citations: 0 • Saves: 1 • Shares: 1

Intracellular polarization of RNAs and proteins in the human small intestinal epithelium

Roy Novoselsky, Yotam Harnik, Oran Yakubovsky, Corine Katina, Yishai Levin, Keren Bahar Halpern, Niv Pencovich, Ido Nachmany, Shalev Itzkovitz

Short Reports | published 02 Dec 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002942

Views: 1569 • Citations: 1 • Saves: 1 • Shares: 13

Mitochondrial calcium uptake orchestrates vertebrate pigmentation via transcriptional regulation of keratin filaments

Jyoti Tanwar, Kriti Ahuja, Akshay Sharma, Paras Sehgal, Gyan Ranjan, Farina Sultan, Anushka Agrawal, Donato D’Angelo, Anshu Priya, Vamsi K. Yenamandra, Archana Singh, Anna Raffaello, Muniswamy Madesh, Rosario Rizzuto, Sridhar Sivasubbu, Rajender K. Motiani

Research Article | published 11 Nov 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002895

Views: 2379 • Citations: 4 • Saves: 13 • Shares: 20

Ortholog of autism candidate gene RBM27 regulates mitoribosomal assembly factor MALS-1 to protect against mitochondrial dysfunction and axon degeneration during neurodevelopment

Tamjid A. Chowdhury, David A. Luy, Garrett Scapellato, Dorian Farache, Amy S. Y. Lee, Christopher C. Quinn

Research Article | published 31 Oct 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002876

Views: 1904 • Citations: 0 • Saves: 4 • Shares: 2

MICU2 up-regulation enhances tumor aggressiveness and metabolic reprogramming during colorectal cancer development

Alison Robert, David Crottès, Jérôme Bourgeais, Naig Gueguen, Arnaud Chevrollier, Jean-François Dumas, Stéphane Servais, Isabelle Domingo, Stéphanie Chadet, Julien Sobilo, Olivier Hérault, Thierry Lecomte, Christophe Vandier, William Raoul, Maxime Guéguinou

Research Article | published 28 Oct 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002854

Views: 1998 • Citations: 0 • Saves: 4 • Shares: 1

Organelle landscape analysis using a multiparametric particle-based method

Yoshitaka Kurikawa, Ikuko Koyama-Honda, Norito Tamura, Seiichi Koike, Noboru Mizushima

Methods and Resources | published 17 Sep 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002777

Views: 2185 • Citations: 1 • Saves: 0 • Shares: 3

A somatic view of the genomic impact of mitochondrial endosymbiosis

Rose M. Doss, Martin W. Breuss

Primer | published 23 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002756

Views: 1171 • Citations: 0 • Saves: 0 • Shares: 4

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

Weichen Zhou, Kalpita R. Karan, Wenjin Gu, Hans-Ulrich Klein, Gabriel Sturm, Philip L. De Jager, David A. Bennett, Michio Hirano, Martin Picard, Ryan E. Mills

Research Article | published 22 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002723

Views: 13716 • Citations: 11 • Saves: 38 • Shares: 206

Adenosine diphosphate released from stressed cells triggers mitochondrial transfer to achieve tissue homeostasis

Hao Li, Hongping Yu, Delin Liu, Peng Liao, Chuan Gao, Jian Zhou, Jialun Mei, Yao Zong, Peng Ding, Meng Yao, Bingqi Wang, Yafei Lu, Yigang Huang, Youshui Gao, Changqing Zhang, Minghao Zheng, Junjie Gao

Research Article | published 20 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002753

Views: 1915 • Citations: 1 • Saves: 10 • Shares: 9

To transfer mitochondria or not to transfer mitochondria: ADP does the trick

Jaromir Novak, Jiri Neuzil

Primer | published 15 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002754

Views: 1468 • Citations: 0 • Saves: 5 • Shares: 0

Pam16 and Pam18 were repurposed during Trypanosoma brucei evolution to regulate the replication of mitochondrial DNA

Corinne von Känel, Philip Stettler, Carmela Esposito, Stephan Berger, Simona Amodeo, Silke Oeljeklaus, Salvatore Calderaro, Ignacio M. Durante, Vendula Rašková, Bettina Warscheid, André Schneider

Research Article | published 15 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002449

Views: 1160 • Citations: 0 • Saves: 1 • Shares: 0

Arl2 GTPase associates with the centrosomal protein Cdk5rap2 to regulate cortical development via microtubule organization

Dongliang Ma, Kun-Yang Lin, Divya Suresh, Jiaen Lin, Mahekta R. Gujar, Htet Yamin Aung, Ye Sing Tan, Yang Gao, Anselm S. Vincent, Teng Chen, Hongyan Wang

Research Article | published 13 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002751

Views: 1606 • Citations: 0 • Saves: 4 • Shares: 1

Alternative TSS use is widespread in Cryptococcus fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1

Thi Tuong Vi Dang, Corinne Maufrais, Jessie Colin, Frédérique Moyrand, Isabelle Mouyna, Jean-Yves Coppée, Chinaemerem U. Onyishi, Joanna Lipecka, Ida Chiara Guerrera, Robin C. May, Guilhem Janbon

Research Article | published 25 Jul 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002724

Views: 1791 • Citations: 1 • Saves: 2 • Shares: 0

Beyond fission and fusion—Diving into the mysteries of mitochondrial shape

Noga Preminger, Maya Schuldiner

Unsolved Mystery | published 01 Jul 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002671

Views: 4533 • Citations: 5 • Saves: 27 • Shares: 3

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March 2025
SuMoTuWeThFrSa
2324252627281
2345678
9101112131415
16171819202122
23242526272829
303112345