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New solutions for antibiotic discovery: Prioritizing microbial biosynthetic space using ecology and machine learning

Marnix H. Medema, Gilles P. van Wezel

Perspective | published 28 Feb 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3003058

Views: 1229 • Citations: 1 • Saves: 3 • Shares: 1

Mining biology for antibiotic discovery

Cesar de la Fuente-Nunez

Perspective | published 26 Nov 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002946

Views: 1937 • Citations: 1 • Saves: 7 • Shares: 9

Harnessing plant biosynthesis for the development of next-generation therapeutics

Philip Spence, James Reed, Anne Osbourn

Perspective | published 05 Nov 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002886

Views: 1407 • Citations: 1 • Saves: 3 • Shares: 1

Cell senescence, the senescence-associated secretory phenotype, and cancers

Larissa G. P. Langhi Prata, Tamar Tchkonia, James L. Kirkland

Perspective | published 21 Sep 2023 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002326

Views: 3260 • Citations: 11 • Saves: 22 • Shares: 10

A multi-lab experimental assessment reveals that replicability can be improved by using empirical estimates of genotype-by-lab interaction

Iman Jaljuli, Neri Kafkafi, Eliezer Giladi, Ilan Golani, Illana Gozes, Elissa J. Chesler, Molly A. Bogue, Yoav Benjamini

Meta-Research Article | published 01 May 2023 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002082

Views: 2231 • Citations: 3 • Saves: 8 • Shares: 8

The future is bright, the future is biotechnology

Richard Hodge, on behalf of the PLOS Biology staff editors

Editorial | published 28 Apr 2023 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002135

Views: 7838 • Citations: 1 • Saves: 16 • Shares: 6

Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery

Brian M. Sweis, Eric J. Nestler

Perspective | published 08 Dec 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001904

Views: 2187 • Citations: 7 • Saves: 12 • Shares: 16

The antimicrobial resistance crisis needs action now

Nonia Pariente, on behalf of the PLOS Biology Staff Editors

Editorial | published 23 Nov 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001918

Views: 10186 • Citations: 15 • Saves: 55 • Shares: 40

A novel class of antimicrobial drugs selectively targets a Mycobacterium tuberculosis PE-PGRS protein

Hoonhee Seo, Sukyung Kim, Hafij Al Mahmud, Md Imtiazul Islam, Youjin Yoon, Hyun-Deuk Cho, Kung-Woo Nam, Jiwon Choi, Young Sig Gil, Byung-Eui Lee, Ho-Yeon Song

Research Article | published 31 May 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001648

Views: 5499 • Citations: 7 • Saves: 24 • Shares: 40

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

Tom G. Richardson, Genevieve M. Leyden, Qin Wang, Joshua A. Bell, Benjamin Elsworth, George Davey Smith, Michael V. Holmes

Methods and Resources | published 25 Feb 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001547

Views: 10781 • Citations: 180 • Saves: 87 • Shares: 27

Empowering grassroots innovation to accelerate biomedical research

Bastian Greshake Tzovaras, Michael Rera, Edwin H. Wintermute, Katharina Kloppenborg, Juliette Ferry-Danini, Guy Aidelberg, Rachel Aronoff, Ariel Lindner, Dusan Misevic

Perspective | published 09 Aug 2021 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001349

Views: 3982 • Citations: 7 • Saves: 11 • Shares: 40

Targeting Mycobacterium tuberculosis response to environmental cues for the development of effective antitubercular drugs

Richard C. Lavin, Calvin Johnson, Yong-Mo Ahn, Kyle M. Kremiller, Matthew Sherwood, Jimmy S. Patel, Yan Pan, Riccardo Russo, Nathan J. MacGilvary, David Giacalone, Yuzo L. Kevorkian, Matthew D. Zimmerman, J. Fraser Glickman, Joel S. Freundlich, Shumin Tan

Discovery Report | published 28 Jul 2021 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001355

Views: 14048 • Citations: 16 • Saves: 17 • Shares: 18

Preregistration of exploratory research: Learning from the golden age of discovery

Ulrich Dirnagl

Perspective | published 26 Mar 2020 PLOS Biology

https://doi.org/10.1371/journal.pbio.3000690

Views: 9598 • Citations: 50 • Saves: 83 • Shares: 25

Applying the science of measurement to biology: Why bother?

Carmen H. Coxon, Colin Longstaff, Chris Burns

Perspective | published 20 Jun 2019 PLOS Biology

https://doi.org/10.1371/journal.pbio.3000338

Views: 7891 • Citations: 22 • Saves: 58 • Shares: 5

Resistance diagnostics as a public health tool to combat antibiotic resistance: A model-based evaluation

David McAdams, Kristofer Wollein Waldetoft, Christine Tedijanto, Marc Lipsitch, Sam P. Brown

Research Article | published 16 May 2019 PLOS Biology

https://doi.org/10.1371/journal.pbio.3000250

Views: 9620 • Citations: 33 • Saves: 116 • Shares: 28

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March 2025
SuMoTuWeThFrSa
2324252627281
2345678
9101112131415
16171819202122
23242526272829
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