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Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles

Sol Vendrell-Fernández, Beatriz Beamud, Yasmina Abou Haydar, Jorge Am de Sousa, Julien Burlaud-Gaillard, Etienne Kornobis, Bertrand Raynal, Joelle Vinh, David Bikard, Jean-Marc Ghigo

Short Reports | published 31 Mar 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002787

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Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression

Ankita Chavan, Lena Skrutl, Federico Uliana, Melanie Pfister, Franziska Brändle, Laszlo Tirian, Delora Baptista, Dominik Handler, David Burke, Anna Sintsova, Pedro Beltrao, Julius Brennecke, Madhav Jagannathan

Methods and Resources | published 15 Jan 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002984

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SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans

Cátia A. Carvalho, Ulrike Bening Abu-Shach, Asha Raju, Zlata Vershinin, Dan Levy, Mike Boxem, Limor Broday

Research Article | published 06 Jan 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002980

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Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron

G. Robert Aguilar, Berta Vidal, Hongzhu Ji, Joke Evenblij, Chien-Po Liao, Hongfei Ji, Giulio Valperga, Christopher Fang-Yen, Oliver Hobert

Research Article | published 06 Jan 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002979

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Cell wall components of gut commensal bacteria stimulate peritrophic matrix formation in malaria vector mosquitoes through activation of the IMD pathway

Xiumei Song, Han Zhou, Jingwen Wang

Research Article | published 06 Jan 2025 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002967

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Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming

Matthew L. Lawton, Melissa M. Inge, Benjamin C. Blum, Erika L. Smith-Mahoney, Dante Bolzan, Weiwei Lin, Christina McConney, Jacob Porter, Jarrod Moore, Ahmed Youssef, Yashasvi Tharani, Xaralabos Varelas, Gerald V. Denis, Wilson W. Wong, Dzmitry Padhorny, Dima Kozakov, Trevor Siggers, Stefan Wuchty, Jennifer Snyder-Cappione, Andrew Emili

Research Article | published 17 Dec 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002943

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Quorum sensing in Vibrio controls carbon metabolism to optimize growth in changing environmental conditions

Chelsea A. Simpson, Zach R. Celentano, Nicholas W. Haas, James B. McKinlay, Carey D. Nadell, Julia C. van Kessel

Research Article | published 11 Nov 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002891

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Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors

Ruth M. Williams, Guneş Taylor, Irving T. C. Ling, Ivan Candido-Ferreira, Daniel M. Fountain, Sarah Mayes, Perihan Seda Ateş-Kalkan, Julianna O. Haug, Andrew J. Price, Sean A. McKinney, Yavor K. Bozhilovh, Richard C. V. Tyser, Shankar Srinivas, Jim R. Hughes, Tatjana Sauka-Spengler

Research Article | published 17 Oct 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002786

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Mycobacteria that cause tuberculosis have retained ancestrally acquired genes for the biosynthesis of chemically diverse terpene nucleosides

Jacob A. Mayfield, Sahadevan Raman, Alexandrea K. Ramnarine, Vivek K. Mishra, Annie D. Huang, Sandrine Dudoit, Jeffrey Buter, Tan-Yun Cheng, David C. Young, Yashodhan M. Nair, Isobel G. Ouellet, Braden T. Griebel, Shuyi Ma, David R. Sherman, Ludovic Mallet, Kyu Y. Rhee, Adriaan J. Minnaard, D. Branch Moody

Research Article | published 30 Sep 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002813

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Metabolic reprogramming during Candida albicans planktonic-biofilm transition is modulated by the transcription factors Zcf15 and Zcf26

Laxmi Shanker Rai, Murielle Chauvel, Hiram Sanchez, Lasse van Wijlick, Corinne Maufrais, Thomas Cokelaer, Natacha Sertour, Mélanie Legrand, Kaustuv Sanyal, David R. Andes, Sophie Bachellier-Bassi, Christophe d’Enfert

Research Article | published 21 Jun 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002693

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KCNK1 promotes proliferation and metastasis of breast cancer cells by activating lactate dehydrogenase A (LDHA) and up-regulating H3K18 lactylation

Xiangchan Hou, Jiawei Ouyang, Le Tang, Pan Wu, Xiangying Deng, Qijia Yan, Lei Shi, Songqing Fan, Chunmei Fan, Can Guo, Qianjin Liao, Yong Li, Wei Xiong, Guiyuan Li, Zhaoyang Zeng, Fuyan Wang

Research Article | published 21 Jun 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002666

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Engineering of a high-fidelity Cas12a nuclease variant capable of allele-specific editing

Jingjing Wei, Jingtong Liu, Ziwen Wang, Yuan Yang, Yuwen Tian, Shengzhou Wang, Bao-Qing Gao, Song Gao, Li Yang, Junnan Tang, Yongming Wang

Research Article | published 12 Jun 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002680

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Engineering of a compact, high-fidelity EbCas12a variant that can be packaged with its crRNA into an all-in-one AAV vector delivery system

Hongjian Wang, Jin Zhou, Jun Lei, Guosheng Mo, Yankang Wu, Huan Liu, Ziyan Pang, Mingkun Du, Zihao Zhou, Chonil Paek, Zaiqiao Sun, Yongshun Chen, Yan Wang, Peng Chen, Lei Yin

Short Reports | published 30 May 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002619

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Multiple checkpoints ensure ribosomes have the correct end

Jacob Gordon, Robin E. Stanley

Primer | published 30 Apr 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002603

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The mechanism of cytoplasmic incompatibility is conserved in Wolbachia-infected Aedes aegypti mosquitoes deployed for arbovirus control

Rupinder Kaur, Cole J. Meier, Elizabeth A. McGraw, Julian F. Hillyer, Seth R. Bordenstein

Update Article | published 28 Mar 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002573

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