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Both pathogen and host dynamically adapt pH responses along the intestinal tract during enteric bacterial infection

Sarah E. Woodward, Laurel M. P. Neufeld, Jorge Peña-Díaz, Wenny Feng, Antonio Serapio-Palacios, Isabel Tarrant, Wanyin Deng, B. Brett Finlay

Research Article | published 15 Aug 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002761

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Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1β

Mor Zigdon, Jasmin Sawaed, Lilach Zelik, Dana Binyamin, Shira Ben-Simon, Nofar Asulin, Rachel Levin, Sonia Modilevsky, Maria Naama, Shahar Telpaz, Elad Rubin, Aya Awad, Wisal Sawaed, Sarina Harshuk-Shabso, Meital Nuriel-Ohayon, Mathumathi Krishnamohan, Michal Werbner, Omry Koren, Sebastian E. Winter, Ron N. Apte, Elena Voronov, Shai Bel

Research Article | published 18 Jan 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002486

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Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

Christopher H. Connor, Amanda Z. Zucoloto, John T. Munnoch, Ian-Ling Yu, Jukka Corander, Paul A. Hoskisson, Braedon McDonald, Alan McNally

Discovery Report | published 17 Oct 2023 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002329

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Atlas of the anatomical localization of atypical chemokine receptors in healthy mice

Serena Melgrati, Egle Radice, Rafet Ameti, Elin Hub, Sylvia Thelen, Pawel Pelczar, David Jarrossay, Antal Rot, Marcus Thelen

Methods and Resources | published 09 May 2023 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002111

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Variable susceptibility of intestinal organoid–derived monolayers to SARS-CoV-2 infection

Kyung Ku Jang, Maria E. Kaczmarek, Simone Dallari, Ying-Han Chen, Takuya Tada, Jordan Axelrad, Nathaniel R. Landau, Kenneth A. Stapleford, Ken Cadwell

Short Reports | published 31 Mar 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001592

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Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage

Yannik Bollen, Joris H. Hageman, Petra van Leenen, Lucca L. M. Derks, Bas Ponsioen, Julian R. Buissant des Amorie, Ingrid Verlaan-Klink, Myrna van den Bos, Leon W. M. M. Terstappen, Ruben van Boxtel, Hugo J. G. Snippert

Methods and Resources | published 28 Jan 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001527

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Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing

Guadalupe J. Jasso, Alok Jaiswal, Mukund Varma, Tyler Laszewski, Angelo Grauel, Abdifatah Omar, Nilsa Silva, Glenn Dranoff, Jeffrey A. Porter, Keith Mansfield, Viviana Cremasco, Aviv Regev, Ramnik J. Xavier, Daniel B. Graham

Research Article | published 27 Jan 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001532

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Gut bacteria-derived 5-hydroxyindole is a potent stimulant of intestinal motility via its action on L-type calcium channels

Barbora Waclawiková, Amber Bullock, Markus Schwalbe, Carmen Aranzamendi, Sieger A. Nelemans, Gertjan van Dijk, Sahar El Aidy

Research Article | published 22 Jan 2021 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001070

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Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis

Michael David Brügger, Tomas Valenta, Hassan Fazilaty, George Hausmann, Konrad Basler

Short Reports | published 11 Dec 2020 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001032

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Quantitative assessment of cell population diversity in single-cell landscapes

Qi Liu, Charles A. Herring, Quanhu Sheng, Jie Ping, Alan J. Simmons, Bob Chen, Amrita Banerjee, Wei Li, Guoqiang Gu, Robert J. Coffey, Yu Shyr, Ken S. Lau

Methods and Resources | published 22 Oct 2018 PLOS Biology

https://doi.org/10.1371/journal.pbio.2006687

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The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile

Jesse Lyons, Phaedra C. Ghazi, Alina Starchenko, Alessio Tovaglieri, Katherine R. Baldwin, Emily J. Poulin, Jessica J. Gierut, Casie Genetti, Vijay Yajnik, David T. Breault, Douglas A. Lauffenburger, Kevin M. Haigis

Research Article | published 29 Mar 2018 PLOS Biology

https://doi.org/10.1371/journal.pbio.2002417

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Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells

Colin R. Lickwar, J. Gray Camp, Matthew Weiser, Jordan L. Cocchiaro, David M. Kingsley, Terrence S. Furey, Shehzad Z. Sheikh, John F. Rawls

Research Article | published 29 Aug 2017 PLOS Biology

https://doi.org/10.1371/journal.pbio.2002054

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Revised Estimates for the Number of Human and Bacteria Cells in the Body

Ron Sender, Shai Fuchs, Ron Milo

Essay | published 19 Aug 2016 PLOS Biology

https://doi.org/10.1371/journal.pbio.1002533

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Fecal Transplants: What Is Being Transferred?

Diana P. Bojanova, Seth R. Bordenstein

Essay | published 12 Jul 2016 PLOS Biology

https://doi.org/10.1371/journal.pbio.1002503

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Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche

Alistair J. Langlands, Axel A. Almet, Paul L. Appleton, Ian P. Newton, James M. Osborne, Inke S. Näthke

Research Article | published 27 Jun 2016 PLOS Biology

https://doi.org/10.1371/journal.pbio.1002491

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