Search Results | PLOS Biology

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease

Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A. Davis, John C. Morris, Celeste M. Karch, Richard J. Perrin, Bruno A. Benitez, Oscar Harari

Research Article | published 30 Apr 2024 PLOS Biology

https://doi.org/10.1371/journal.pbio.3002607

Views: 6415 • Citations: 10 • Saves: 45 • Shares: 11

If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?

Christian Haass, Dennis Selkoe

Unsolved Mystery | published 21 Jul 2022 PLOS Biology

https://doi.org/10.1371/journal.pbio.3001694

Views: 19810 • Citations: 101 • Saves: 163 • Shares: 279

A proteomic atlas of senescence-associated secretomes for aging biomarker development

Nathan Basisty, Abhijit Kale, Ok Hee Jeon, Chisaka Kuehnemann, Therese Payne, Chirag Rao, Anja Holtz, Samah Shah, Vagisha Sharma, Luigi Ferrucci, Judith Campisi, Birgit Schilling

Methods and Resources | published 16 Jan 2020 PLOS Biology

https://doi.org/10.1371/journal.pbio.3000599

Views: 64318 • Citations: 975 • Saves: 855 • Shares: 64

Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity

Tania Carrillo-Roa, Christiana Labermaier, Peter Weber, David P. Herzog, Caleb Lareau, Sara Santarelli, Klaus V. Wagner, Monika Rex-Haffner, Daniela Harbich, Sebastian H. Scharf, Charles B. Nemeroff, Boadie W. Dunlop, W. Edward Craighead, Helen S. Mayberg, Mathias V. Schmidt, Manfred Uhr, Florian Holsboer, Inge Sillaber, Elisabeth B. Binder, Marianne B. Müller

Research Article | published 28 Dec 2017 PLOS Biology

https://doi.org/10.1371/journal.pbio.2002690

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Putting placebos to the test