Physiologic signatures within six hours of hospitalization identify acute illness phenotypes

• Yuanfang Ren,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-4716-2408

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• Tyler J. Loftus,

  Roles Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Surgery, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0001-5354-443X

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• Yanjun Li,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Computer & Information Science & Engineering, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-6277-4189

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• Ziyuan Guan,

  Roles Data curation, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America

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• Matthew M. Ruppert,

  Roles Data curation, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0001-9757-4454

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• Shounak Datta,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-4040-0514

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• Gilbert R. Upchurch Jr.,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Surgery, University of Florida, Gainesville, Florida, United States of America

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• Patrick J. Tighe,

  Roles Writing – review & editing

  Affiliation Department of Anesthesiology, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-1881-9941

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• Parisa Rashidi,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0003-4530-2048

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• Benjamin Shickel,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-5304-7027

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• Tezcan Ozrazgat-Baslanti ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors contributed equally as senior authors.

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America, Sepsis and Critical Illness Research Center, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-1158-9928

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• Azra Bihorac

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: abihorac@ufl.edu

  ¶‡ These authors contributed equally as senior authors.

  Affiliations Intelligent Critical Care Center (IC3), University of Florida, Gainesville, Florida, United States of America, Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, United States of America, Department of Surgery, University of Florida, Gainesville, Florida, United States of America, Sepsis and Critical Illness Research Center, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-5745-2863

  ⨯