An explainable artificial intelligence approach for predicting cardiovascular outcomes using electronic health records

• Sergiusz Wesołowski ,

  Contributed equally to this work with: Sergiusz Wesołowski, Gordon Lemmon

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Human Genetics and Utah Center for Genetic Discovery, University of Utah, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0002-9560-723X

  ⨯
• Gordon Lemmon ,

  Contributed equally to this work with: Sergiusz Wesołowski, Gordon Lemmon

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

  Affiliation Department of Human Genetics and Utah Center for Genetic Discovery, University of Utah, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0002-8381-205X

  ⨯
• Edgar J. Hernandez,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft

  Affiliation Department of Human Genetics and Utah Center for Genetic Discovery, University of Utah, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0003-1455-8251

  ⨯
• Alex Henrie,

  Roles Data curation, Formal analysis, Software, Validation, Visualization

  Affiliation Department of Human Genetics and Utah Center for Genetic Discovery, University of Utah, Salt Lake City, UT, United States of America

  ⨯
• Thomas A. Miller,

  Roles Conceptualization, Data curation, Investigation, Validation, Writing – original draft

  Affiliation Division of Pediatric Cardiology, University of Utah School of Medicine, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0001-5498-7021

  ⨯
• Derek Weyhrauch,

  Roles Investigation, Validation, Visualization, Writing – original draft

  Affiliation Division of Pediatric Cardiology, University of Utah School of Medicine, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0002-9059-4062

  ⨯
• Michael D. Puchalski,

  Roles Data curation, Project administration, Resources, Writing – original draft

  Affiliation Division of Pediatric Cardiology, University of Utah School of Medicine, Salt Lake City, UT, United States of America

  ⨯
• Bruce E. Bray,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

  Affiliations Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, UT, United States of America, University of Utah, Biomedical Informatics, Salt Lake City, UT 84108, United States of America

  https://orcid.org/0000-0003-3963-2964

  ⨯
• Rashmee U. Shah,

  Roles Data curation, Validation, Visualization, Writing – original draft

  Affiliation Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0002-7823-8540

  ⨯
• Vikrant G. Deshmukh,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Validation

  Affiliation University of Utah Health Care CMIO Office, Salt Lake City, UT, United States of America

  ⨯
• Rebecca Delaney,

  Roles Validation, Writing – original draft

  Affiliation Department of Population Health Sciences, University of Utah, Salt Lake City, UT, United States of America

  ⨯
• H. Joseph Yost,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft

  Affiliation Molecular Medicine Program, University of Utah, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0003-2961-5669

  ⨯
• Karen Eilbeck,

  Roles Conceptualization, Funding acquisition, Project administration, Validation, Visualization, Writing – original draft

  Affiliation Department of Population Health Sciences, University of Utah, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0002-0831-6427

  ⨯
• Martin Tristani-Firouzi ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Supervision, Visualization, Writing – original draft

  * E-mail: Martin.Tristani@utah.edu (MTF); myandell@genetics.utah.edu (MY)

  Affiliations Division of Pediatric Cardiology, University of Utah School of Medicine, Salt Lake City, UT, United States of America, Nora Eccles Harrison CVRTI, University of Utah School of Medicine, Salt Lake City, UT, United States of America

  https://orcid.org/0000-0001-5916-442X

  ⨯
• Mark Yandell

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft

  * E-mail: Martin.Tristani@utah.edu (MTF); myandell@genetics.utah.edu (MY)

  Affiliation Department of Human Genetics and Utah Center for Genetic Discovery, University of Utah, Salt Lake City, UT, United States of America

  ⨯