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Open Access
Peer-reviewed
Research Article
Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense
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Philip O. Scumpia ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: smale@mednet.ucla.edu (STS); pscumpia@mednet.ucla.edu (POS)
Affiliation Department of Medicine, Division of Dermatology, University of California at Los Angeles, Los Angeles, California, United States of America
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Giovanni A. Botten,
Roles Data curation, Formal analysis, Investigation
Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America
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Joshua S. Norman,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America
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Kindra M. Kelly-Scumpia,
Roles Data curation, Formal analysis, Investigation
Affiliation Department of Medicine, Division of Dermatology, University of California at Los Angeles, Los Angeles, California, United States of America
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Roberto Spreafico,
Roles Formal analysis, Resources
Current address: Synthetic Genomics, Inc. La Jolla, California, United States of America
Affiliations Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America, Institute for Quantitative and Computational Biosciences, University of California at Los Angeles, Los Angeles, California, United States of America
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Amber R. Ruccia,
Roles Formal analysis, Validation
Affiliation Department of Medicine, Division of Dermatology, University of California at Los Angeles, Los Angeles, California, United States of America
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Prabhat K. Purbey,
Roles Formal analysis, Validation
Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America
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Brandon J. Thomas,
Roles Data curation, Formal analysis
Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America
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Robert L. Modlin,
Roles Resources, Supervision
Affiliations Department of Medicine, Division of Dermatology, University of California at Los Angeles, Los Angeles, California, United States of America, Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America
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Stephen T. Smale
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: smale@mednet.ucla.edu (STS); pscumpia@mednet.ucla.edu (POS)
Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California, United States of America
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Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense
- Philip O. Scumpia,
- Giovanni A. Botten,
- Joshua S. Norman,
- Kindra M. Kelly-Scumpia,
- Roberto Spreafico,
- Amber R. Ruccia,
- Prabhat K. Purbey,
- Brandon J. Thomas,
- Robert L. Modlin,
- Stephen T. Smale
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- Published: July 13, 2017
- https://doi.org/10.1371/journal.ppat.1006496