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Table of Contents: June 2016

False-color electron micrograph depicting bacteria (blue) and the DNA-based trap (yellow). Tran et al.

Image Credit: Tran et al.

Opinions

The Janus-Face of Bacteriophages across Human Body Habitats

Adam Wahida, Klaus Ritter, Hans-Peter Horz

Research Articles

TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response

Raquel Espín-Palazón, Alicia Martínez-López, Francisco J. Roca, Azucena López-Muñoz, Sylwia D. Tyrkalska, Sergio Candel, Diana García-Moreno, Alberto Falco, José Meseguer, Amparo Estepa, Victoriano Mulero

Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody

Ning Chai, Lee R. Swem, Mike Reichelt, Haiyin Chen-Harris, Elizabeth Luis, Summer Park, Ashley Fouts, Patrick Lupardus, Thomas D. Wu, Olga Li, Jacqueline McBride, Michael Lawrence, Min Xu, Man-Wah Tan

VgrG and PAAR Proteins Define Distinct Versions of a Functional Type VI Secretion System

Francesca R. Cianfanelli, Juliana Alcoforado Diniz, Manman Guo, Virginia De Cesare, Matthias Trost, Sarah J. Coulthurst

A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

Géraldine Arrode-Brusés, Diana Goode, Kyle Kleinbeck, Jolanta Wilk, Ines Frank, Siddappa Byrareddy, James Arthos, Brooke Grasperge, James Blanchard, Thomas Zydowsky, Agegnehu Gettie, Elena Martinelli

Related Articles

  1. Correction: A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

Lytic Promoters Express Protein during Herpes Simplex Virus Latency

Tiffany A. Russell, David C. Tscharke

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection

Anna A. Müller, Tamas Dolowschiak, Mikael E. Sellin, Boas Felmy, Carolin Verbree, Sandra Gadient, Alexander J. Westermann, Jörg Vogel, Salome LeibundGut-Landmann, Wolf-Dietrich Hardt

Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza

Veronika I. Zarnitsyna, Jennie Lavine, Ali Ellebedy, Rafi Ahmed, Rustom Antia

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus

Rupkatha Mukhopadhyay, Sujayita Roy, Rajkumar Venkatadri, Yu-Pin Su, Wenjuan Ye, Elena Barnaeva, Lesley Mathews Griner, Noel Southall, Xin Hu, Amy Q. Wang, Xin Xu, Andrés E. Dulcey, Juan J. Marugan, Marc Ferrer, Ravit Arav-Boger

The WOPR Protein Ros1 Is a Master Regulator of Sporogenesis and Late Effector Gene Expression in the Maize Pathogen Ustilago maydis

Marie Tollot, Daniela Assmann, Christian Becker, Janine Altmüller, Julien Y. Dutheil, Carl-Eric Wegner, Regine Kahmann

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

Timothy J. Nice, Lisa C. Osborne, Vesselin T. Tomov, David Artis, E. John Wherry, Herbert W. Virgin

KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection

Adarsh Dharan, Sarah Talley, Abhishek Tripathi, João I. Mamede, Matthias Majetschak, Thomas J. Hope, Edward M. Campbell

Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals

Agustina Taglialegna, Susanna Navarro, Salvador Ventura, James A. Garnett, Steve Matthews, José R. Penades, Iñigo Lasa, Jaione Valle

Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair

Jennifer Quantius, Carole Schmoldt, Ana I. Vazquez-Armendariz, Christin Becker, Elie El Agha, Jochen Wilhelm, Rory E. Morty, István Vadász, Konstantin Mayer, Stefan Gattenloehner, Ludger Fink, Mikhail Matrosovich, Xiaokun Li, Werner Seeger, Juergen Lohmeyer, Saverio Bellusci, Susanne Herold

Superparasitism Drives Heritable Symbiont Epidemiology and Host Sex Ratio in a Wasp

Steven R. Parratt, Crystal L. Frost, Martijn A. Schenkel, Annabel Rice, Gregory D. D. Hurst, Kayla C. King

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

Ashwanth C. Francis, Mariana Marin, Jiong Shi, Christopher Aiken, Gregory B. Melikyan

CLCuMuB βC1 Subverts Ubiquitination by Interacting with NbSKP1s to Enhance Geminivirus Infection in Nicotiana benthamiana

Qi Jia, Na Liu, Ke Xie, Yanwan Dai, Shaojie Han, Xijuan Zhao, Lichao Qian, Yunjing Wang, Jinping Zhao, Rena Gorovits, Daoxin Xie, Yiguo Hong, Yule Liu

Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement

Michael A. Schmid, Dustin R. Glasner, Sanjana Shah, Daniela Michlmayr, Laura D. Kramer, Eva Harris

Bacillus anthracis Spore Surface Protein BclA Mediates Complement Factor H Binding to Spores and Promotes Spore Persistence

Yanyu Wang, Sarah A. Jenkins, Chunfang Gu, Ankita Shree, Margarita Martinez-Moczygemba, Jennifer Herold, Marina Botto, Rick A. Wetsel, Yi Xu

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

Simone A. Joosten, Krista E. van Meijgaarden, Franca del Nonno, Andrea Baiocchini, Linda Petrone, Valentina Vanini, Hermelijn H. Smits, Fabrizio Palmieri, Delia Goletti, Tom H. M. Ottenhoff

Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein

Yaiza Fernández-García, Juan Reguera, Carola Busch, Gregor Witte, Oliberto Sánchez-Ramos, Christian Betzel, Stephen Cusack, Stephan Günther, Sophia Reindl

Related Articles

  1. Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells

Laura Berneking, Marie Schnapp, Andreas Rumm, Claudia Trasak, Klaus Ruckdeschel, Malik Alawi, Adam Grundhoff, Alexey G. Kikhney, Friedrich Koch-Nolte, Friedrich Buck, Markus Perbandt, Christian Betzel, Dmitri I. Svergun, Moritz Hentschke, Martin Aepfelbacher

Cooperation between Monocyte-Derived Cells and Lymphoid Cells in the Acute Response to a Bacterial Lung Pathogen

Andrew S. Brown, Chao Yang, Ka Yee Fung, Annabell Bachem, Dorothée Bourges, Sammy Bedoui, Elizabeth L. Hartland, Ian R. van Driel

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles

Katja Koeppen, Thomas H. Hampton, Michael Jarek, Maren Scharfe, Scott A. Gerber, Daniel W. Mielcarz, Elora G. Demers, Emily L. Dolben, John H. Hammond, Deborah A. Hogan, Bruce A. Stanton

Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection

Sarah E. Clark, Holly C. Filak, Brandon S. Guthrie, Rebecca L. Schmidt, Amanda Jamieson, Patricia Merkel, Vijaya Knight, Caroline M. Cole, David H. Raulet, Laurel L. Lenz

Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment

Ruben R. Bender, Anke Muth, Irene C. Schneider, Thorsten Friedel, Jessica Hartmann, Andreas Plückthun, Andrea Maisner, Christian J. Buchholz

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii

Clément N. David, Elma S. Frias, Jenny I. Szu, Philip A. Vieira, Jacqueline A. Hubbard, Jonathan Lovelace, Marena Michael, Danielle Worth, Kathryn E. McGovern, Iryna M. Ethell, B. Glenn Stanley, Edward Korzus, Todd A. Fiacco, Devin K. Binder, Emma H. Wilson

Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut

Tingting Wang, Deng Pan, Zhicheng Zhou, Yun You, Changying Jiang, Xueqiang Zhao, Xin Lin

Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection

Fengliang Liu, Xiuzhen Fan, Sarah Auclair, Monique Ferguson, Jiaren Sun, Lynn Soong, Wei Hou, Robert R. Redfield, Deborah L. Birx, Silvia Ratto-Kim, Merlin L. Robb, Jerome H. Kim, Nelson L. Michael, Haitao Hu

Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation

Kendi Okuda, Mei Tong, Brian Dempsey, Kathryn J. Moore, Ricardo T. Gazzinelli, Neal Silverman

Leishmania major Promastigotes Evade LC3-Associated Phagocytosis through the Action of GP63

Christine Matte, Pierre-André Casgrain, Olivier Séguin, Neda Moradin, Wan Jin Hong, Albert Descoteaux

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

Louis S. Ates, Aniek D. van der Woude, Jovanka Bestebroer, Gunny van Stempvoort, René J. P. Musters, Juan J. Garcia-Vallejo, Daisy I. Picavet, Robert van de Weerd, Massimiliano Maletta, Coenraad P. Kuijl, Nicole N. van der Wel, Wilbert Bitter

Small RNA-Based Antiviral Defense in the Phytopathogenic Fungus Colletotrichum higginsianum

Sonia Campo, Kerrigan B. Gilbert, James C. Carrington

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

Mohamed Abdel-Mohsen, Leonard Chavez, Ravi Tandon, Glen M. Chew, Xutao Deng, Ali Danesh, Sheila Keating, Marion Lanteri, Michael L. Samuels, Rebecca Hoh, Jonah B. Sacha, Philip J. Norris, Toshiro Niki, Cecilia M. Shikuma, Mitsuomi Hirashima, Steven G. Deeks, Lishomwa C. Ndhlovu, Satish K. Pillai

Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense

Kan Lin, Kathryn M. O'Brien, Carolina Trujillo, Ruojun Wang, Joshua B. Wallach, Dirk Schnappinger, Sabine Ehrt

S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages

Susan Realegeno, Kindra M. Kelly-Scumpia, Angeline Tilly Dang, Jing Lu, Rosane Teles, Philip T. Liu, Mirjam Schenk, Ernest Y. Lee, Nathan W. Schmidt, Gerard C. L. Wong, Euzenir N. Sarno, Thomas H. Rea, Maria T. Ochoa, Matteo Pellegrini, Robert L. Modlin

Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding

Gopal Sapparapu, Rita Czakó, Gabriela Alvarado, Sreejesh Shanker, B. V. Venkataram Prasad, Robert L. Atmar, Mary K. Estes, James E. Crowe Jr.

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

Ferdy R. van Diemen, Elisabeth M. Kruse, Marjolein J. G. Hooykaas, Carlijn E. Bruggeling, Anita C. Schürch, Petra M. van Ham, Saskia M. Imhof, Monique Nijhuis, Emmanuel J. H. J. Wiertz, Robert Jan Lebbink

Discovery of a Natural Microsporidian Pathogen with a Broad Tissue Tropism in Caenorhabditis elegans

Robert J. Luallen, Aaron W. Reinke, Linda Tong, Michael R. Botts, Marie-Anne Félix, Emily R. Troemel

Research Matters

Lessons from Reverse Translation

Adam S. Lauring