About the Authors

Rob N. de Jong

Contributed equally to this work with: Rob N. de Jong, Frank J. Beurskens

Affiliation Genmab, Utrecht, The Netherlands

Frank J. Beurskens

Contributed equally to this work with: Rob N. de Jong, Frank J. Beurskens

Affiliation Genmab, Utrecht, The Netherlands

Sandra Verploegen

Affiliation Genmab, Utrecht, The Netherlands

Kristin Strumane

Affiliation Genmab, Utrecht, The Netherlands

Muriel D. van Kampen

Affiliation Genmab, Utrecht, The Netherlands

Marleen Voorhorst

Affiliation Genmab, Utrecht, The Netherlands

Wendy Horstman

Affiliation Genmab, Utrecht, The Netherlands

Patrick J. Engelberts

Affiliation Genmab, Utrecht, The Netherlands

Simone C. Oostindie

Affiliation Genmab, Utrecht, The Netherlands

Guanbo Wang

Affiliations Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, Netherlands Proteomics Centre, Utrecht, The Netherlands

Albert J. R. Heck

Affiliations Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, Netherlands Proteomics Centre, Utrecht, The Netherlands

Janine Schuurman

Affiliation Genmab, Utrecht, The Netherlands

Paul W. H. I. Parren

p.parren@genmab.com

Affiliations Genmab, Utrecht, The Netherlands, Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark, Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: RNdJ, FJB, SV, KS, MV, WH, PJE, SCO, MDvK, JS and PWHIP are Genmab employees and own Genmab warrants and/or stock. RNdJ, FJB, JS and PWHIP are inventors on Genmab patent applications. In this manuscript we described the identification of a new antibody platform for the development of therapeutic antibodies, which we have registered under the trade name “HexaBody.”

Author Contributions

Conceived and designed the experiments: RNdJ FJB SV MDvK GW AJRH JS PWHIP. Performed the experiments: RNdJ MV WH PJE SCO GW. Analyzed the data: RNdJ FJB SV MDvK MV WH PJE SCO GW AJRH JS PWHIP. Wrote the paper: RNdJ FJB SV KS AJRH JS PWHIP.