The Female Lower Genital Tract Is a Privileged Compartment with IL-10 Producing Dendritic Cells and Poor Th1 Immunity following Chlamydia trachomatis Infection

Ellen Marks; Miguel A. Tam; Nils Y. Lycke

doi:10.1371/journal.ppat.1001179

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Peer-reviewed

Research Article

The Female Lower Genital Tract Is a Privileged Compartment with IL-10 Producing Dendritic Cells and Poor Th1 Immunity following Chlamydia trachomatis Infection

Ellen Marks,

Affiliation Department of Microbiology and Immunology, Mucosal Immunobiology and Vaccine Center, Institute of Biomedicine, The University of Gothenburg, Gothenburg, Sweden
⨯
Miguel A. Tam,
Nils Y. Lycke

* E-mail: nils.lycke@microbio.gu.se

Affiliation Department of Microbiology and Immunology, Mucosal Immunobiology and Vaccine Center, Institute of Biomedicine, The University of Gothenburg, Gothenburg, Sweden
⨯

The Female Lower Genital Tract Is a Privileged Compartment with IL-10 Producing Dendritic Cells and Poor Th1 Immunity following Chlamydia trachomatis Infection

Ellen Marks,
Miguel A. Tam,
Nils Y. Lycke

Published: November 4, 2010
https://doi.org/10.1371/journal.ppat.1001179

About the Authors

Ellen Marks

Affiliation Department of Microbiology and Immunology, Mucosal Immunobiology and Vaccine Center, Institute of Biomedicine, The University of Gothenburg, Gothenburg, Sweden

Miguel A. Tam

Current address: Division of Biological Sciences, University of California, San Diego, La Jolla, California, United States of America

Nils Y. Lycke

* E-mail: nils.lycke@microbio.gu.se

Affiliation Department of Microbiology and Immunology, Mucosal Immunobiology and Vaccine Center, Institute of Biomedicine, The University of Gothenburg, Gothenburg, Sweden

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EM MAT NYL. Performed the experiments: EM MAT. Analyzed the data: EM. Contributed reagents/materials/analysis tools: NYL. Wrote the paper: EM NYL.

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Chlamydia infection
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T cells
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Chlamydia trachomatis
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Gene expression
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Cytokines
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T helper cells
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Messenger RNA
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Regulatory T cells
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