About the Authors
- Christiane Costa-Pereira
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Roles Data curation, Formal analysis, Methodology, Writing – original draft
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Ana Carolina Campi-Azevedo
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Roles Data curation, Formal analysis, Methodology, Project administration, Writing – original draft
* E-mail: accampi@cpqrr.fiocruz.br (ACCA); oassismartins@gmail.com (OAMF)
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Jordana Grazziela Coelho-dos-Reis
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Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Vanessa Peruhype-Magalhães
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Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Writing – review & editing
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Márcio Sobreira Silva Araújo
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Roles Conceptualization, Investigation, Methodology, Supervision
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Lis Ribeiro do Vale Antonelli
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Roles Data curation, Supervision, Writing – review & editing
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Cristina Toscano Fonseca
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Roles Methodology, Writing – review & editing
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Jandira Aparecida Lemos
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Roles Data curation, Investigation, Methodology, Validation
Affiliation Secretaria de Estado de Saúde, Governo do Estado de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil
- Luiz Cosme Cote Malaquias
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Roles Investigation, Methodology, Resources
Affiliation Universidade Federal de Alfenas, Alfenas, Minas Gerais, Brazil
- Matheus de Souza Gomes
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Roles Data curation
Affiliation Laboratório de Bioinformática e Análises Moleculares, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil
- Laurence Rodrigues Amaral
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Roles Data curation, Formal analysis
Affiliation Laboratório de Bioinformática e Análises Moleculares, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil
- Maria Rios
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Roles Data curation, Supervision, Validation, Writing – review & editing
Affiliation Center for Biologics Evaluation and Research – CBER – Food and Drug Administration (FDA), Silver Spring, Maryland, United States of America
- Caren Chancey
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Roles Data curation, Writing – review & editing
Affiliation Center for Biologics Evaluation and Research – CBER – Food and Drug Administration (FDA), Silver Spring, Maryland, United States of America
- Harold Richard Persi
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Roles Methodology, Resources
Affiliation Instituto de Biologia do Exército, Rio de Janeiro, Rio de Janeiro, Brazil
- Jorge Marcelo Pereira
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Roles Methodology, Resources
Affiliation Instituto de Biologia do Exército, Rio de Janeiro, Rio de Janeiro, Brazil
- Maria de Lourdes de Sousa Maia
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Roles Funding acquisition, Project administration, Resources, Supervision
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Marcos da Silva Freire
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Roles Investigation, Methodology, Resources
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Reinaldo de Menezes Martins
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Roles Investigation, Methodology, Resources
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Akira Homma
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Roles Investigation, Methodology, Resources
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Marisol Simões
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Roles Investigation, Methodology, Resources
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Anna Yoshida Yamamura
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Roles Investigation, Methodology, Resources
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Roberto Henrique Guedes Farias
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Roles Investigation, Methodology, Resources
Affiliation Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos- FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Alessandro Pecego Martins Romano
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Roles Investigation, Methodology, Resources
Affiliation Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Federal District, Brazil
- Carla Magda Domingues
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Roles Funding acquisition, Investigation, Resources, Visualization
Affiliation Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Federal District, Brazil
- Pedro Luiz Tauil
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Roles Investigation, Methodology, Resources
Affiliation Universidade de Brasília, Brasília, Federal District, Brazil
- Pedro Fernando Costa Vasconcelos
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Roles Investigation, Methodology, Resources
Affiliation Instituto Evandro Chagas– IEC, Ananindeua, Pará, Brazil
- Iramaya Rodrigues Caldas
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Roles Investigation, Methodology, Resources
Affiliation Diretoria Regional de Brasília – DIREB, FIOCRUZ, Brasília, Federal District, Brazil
- Luiz Antônio Camacho
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Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation
Affiliation Escola Nacional de Saúde Pública, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil
- Andrea Teixeira-Carvalho
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Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
- Olindo Assis Martins-Filho
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Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing
* E-mail: accampi@cpqrr.fiocruz.br (ACCA); oassismartins@gmail.com (OAMF)
Affiliation Centro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
Competing Interests
Seven participants of this study (MS, MSF, AMYY, AH, RMM, RHGF, MLSM) are employees at the 17DD-YF vaccine manufacturer (Bio-Manguinhos, Fundação Oswaldo Cruz), and nine participants work in other units of Fundação Oswaldo Cruz (ACCA, MSSA, VPM, LRVA, CTF, LABC, IRC, ATC and OAMF). Bias from competing interest was prevented by: (1) one collaboration with a general clinical Physician (HRP) from Brazilian Army, expert in infectious disease; (2) one general clinical Nurse (JACL) expert in vaccine epidemiological vigilance from State Health Department; (3) three Immunologists (LCCM) from Brazilian Research Academy and (MR and CC) from United States Department of Health; and (5) two independent professionals working as PhD student (CCP) or Post-Doc Researchers (JGCR) in the field of infectious diseases. (6) two authors (MSG and LRA) from the Universidade Federal de Alfenas contributed to bioinformatics analysis (decision tree algorithm). The FIOCRUZ extramural coworkers contributed with critical overview of the studystrategy, immunization of volunteers as well as medical care, blood sample collection, blind sample handling and processing, data collection, statistical analysis and data interpretation. The views and opinions expressed here are those of the authors and do not represent the official position of the US FDA.