Journal Information

The first journal solely devoted to the world’s most neglected tropical diseases, PLOS Neglected Tropical Diseases publishes leading research and commentary on all scientific, medical, political and public health aspects of these forgotten diseases affecting the world’s most neglected people.


PLOS Neglected Tropical Diseases publishes research devoted to the pathology, epidemiology, prevention, treatment and control of the neglected tropical diseases (NTDs), as well as public policy relevant to this group of diseases.

The NTDs are defined as a group of poverty-promoting chronic infectious diseases, which primarily occur in rural areas and poor urban areas of low-income and middle-income countries. They are poverty-promoting because of their impact on child health and development, pregnancy, and worker productivity, as well as their stigmatizing features.

All aspects of these diseases are considered, including:

  • Pathogenesis
  • Clinical features
  • Pharmacology and treatment
  • Diagnosis
  • Epidemiology
  • Vector biology
  • Vaccinology and prevention
  • Demographic, ecological and social determinants
  • Public health and policy aspects (including cost-effectiveness analyses)

The journal publishes relevant in vitro and animal studies as well as human investigations.

Major NTDs within scope

Protozoan Infections
  • Amebiasis
  • Balantidiasis
  • Chagas Disease
  • Giardiasis
  • Human African Trypanosomiasis
  • Leishmaniasis
Helminth Infections
  • Taeniasis-Cysticercosis
  • Dracunculiasis
  • Echinococcosis
  • Food-borne Trematodiases
  • Loiasis
  • Lymphatic Filariasis
  • Onchocerciasis
  • Schistosomiasis
  • Soil-transmitted Helminthiases (Ascariasis, Hookworm Diseases, Trichuriasis, Strongyloidiasis)
  • Toxocariasis and other Larva Migrans
Viral Infections
  • Dengue
  • Japanese encephalitis
  • Jungle yellow fever
  • Other arboviral infections
  • Rabies
  • Rift Valley fever
  • Viral hemorrhagic fevers
Bacterial Infections
  • Bartonella
  • Bovine Tuberculosis in Humans
  • Buruli Ulcer
  • Cholera
  • Enteric pathogens (Shigella, Salmonella, E. coli)
  • Leprosy
  • Leptospirosis
  • Relapsing Fever
  • Trachoma
  • Treponematoses (Bejel, Pinta, Syphilis, Yaws)
Fungal Infections
  • Mycetoma
  • Paracoccidiomycosis
Ectoparasitic Infections
  • Scabies
  • Myiasis

Nutritional diseases

Papers that examine the link between nutrition and NTD infection are considered for PLOS Neglected Tropical Diseases.

HIV/AIDS, malaria, and tuberculosis

The “big three” diseases, HIV/AIDS, malaria, and tuberculosis, are not generally considered for PLOS Neglected Tropical Diseases. Submit research on these diseases to one of the six other PLOS journals as appropriate.

Exception: The above three diseases are considered in the context of co-infections with the NTDs. For example, PLOS Neglected Tropical Diseases is interested in manuscripts that explore integrated control of the NTDs and the “big three” diseases. Additionally, PLOS Neglected Tropical Diseases considers manuscripts on all aspects of bovine tuberculosis affecting humans, and, on a case-by-case basis, on vivax malaria and related topics.

Fundamental microbial pathogenesis

Research on fundamental microbial pathogenesis and the molecular and cellular biology of the NTDs pathogens should be submitted to PLOS Pathogens. Examples: fundamental mechanisms of immune evasion by Plasmodium, blocking of apoptosis by Salmonella, population biology of Candida, or latency in herpes viruses.

Research on molecular pathways as potential drug or vaccine targets would be more suitable for PLOS Neglected Tropical Diseases.

Other research more suitable to PLOS Neglected Tropical Diseases includes health product (i.e., drug, diagnostic, and vaccine) development, human immunology, clinical manifestations, surveillance and epidemiologic research, public health control, and health policy aspects of the NTDs.

Other infections

Other infectious diseases will also be considered on a case-by-case basis. Submit a presubmission inquiry for consideration. Authors must indicate in the presubmission inquiry why they consider the infection to be a neglected tropical disease.

Public policy

PLOS Neglected Tropical Diseases is committed to all aspects of the NTDs that are relevant to global public health, including important public policy statements. The magazine section contains opinion pieces, debates, policy papers, expert commentaries on research articles, reviews, problem-based educational articles (from the laboratory, clinic, and field), interviews, and historical profiles and perspectives.


Original research

Research articles consider all aspects of the NTDs, including their pathogenesis, clinical features, pharmacology and treatment, diagnosis, epidemiology, vector biology, and vaccinology and prevention. Demographic, ecological and social determinants, public health, and policy aspects of these diseases (including cost-effectiveness analyses) are also a priority.

Magazine section

  • The Editorial is written by the Editor-in-Chief or a member of the Editorial Board.

  • The Viewpoints section contains opinion pieces grounded in evidence on topics of broad interest to the journal's readership.

  • The Debate section highlights controversial issues in the field of NTDs.

  • The Policy Platform is for authors to discuss policies that could improve the lives of those at risk of, or affected by, the NTDs.

  • The Reviews section is for authors to summarize the best available evidence on a topic relevant to the NTD community.

  • In an Expert Commentary, authors discuss the clinical, policy, public-health, or research implications of a freely available research article.

  • From Innovation to Application is a section in which authors discuss new technologies, including drugs, vaccines, and diagnostics.

  • The Photo Quiz presents a clinical image and brief case discussion followed by questions, learning points, and key references.

  • In the Symposium section, authors discuss a “real world” problem, from the clinic, laboratory, or community, and how best it can be tackled.

  • Historical Profiles & Perspectives look back in history to discuss a notable figure or a control program that worked or failed.

  • Interviews highlight the work of a person who has made a notable contribution to controlling NTDs.

Developing Countries

As part of its mission to widen the distribution of scientific literature, PLOS is particularly concerned with the disparities in access to information between developed and developing countries. PLOS provides immediate, free, and unrestricted access to all the scientific and medical literature that it publishes. In addition, PLOS is also dedicated to establishing a medium for publishing science from the developing world. Thus, a major goal of PLOS Neglected Tropical Diseases is to promote and profile the efforts of researchers, health practitioners, and public-health experts in endemic countries in order to help build science and health capacity in those regions.

PLOS Neglected Tropical Diseases offers the following means of support to authors in developing countries:

  • Publication fee assistance. Read more.

  • Editorial support. PLOS Neglected Tropical Diseases is organized to provide additional editorial support for authors in developing countries. Manuscripts that are accepted for publication will receive additional support from our editorial staff or professionals from our partner organizations.

  • International Editorial Board. About 40% of our Associate Editors—who handle peer review of research articles—are based in developing countries. These experts understand the issues involved in confronting these diseases in their endemic settings, and they will help to ensure that the journal is a voice for researchers in these countries. See the Editorial Board.

  • Worldwide readership. As an Open Access journal, PLOS Neglected Tropical Diseases articles will always be freely available online via the journal Web site as well as through PubMed Central. Our content license means that readers are free to download, print, distribute, and translate your work, provided that they give you credit and cite the source. This means that your work will have the broadest possible audience: the entire world. And recent studies suggest that Open Access articles are downloaded and cited more frequently.

  • Influence. Your research has the chance to be highly influential. Select papers about neglected tropical diseases published in PLOS journals have been downloaded many thousands of times, have been mentioned in international news sources, and have had an important impact on health policy. For example, a paper in PLOS Medicine led to a UN mandate to integrate control of the NTDs into the UN's malaria control efforts.

Criteria for Publication

To be considered for publication in PLOS Neglected Tropical Diseases, any given manuscript must satisfy the following criteria:

  • Originality

  • Importance and relevance to researchers, practitioners, or policy makers in the field of NTDs

  • Interest for researchers or practitioners outside the field

  • Rigorous methodology with conclusions justified by the evidence presented

  • Adherence to the highest ethical standards

Editorial Oversight

The editorial process is run as a partnership between the PLOS Neglected Tropical Diseases Editors-in-Chief, the board of Deputy Editors, and a team of academic experts who act as Associate Editors (AEs). These individuals, all of whom are members of the PLOS Neglected Tropical Diseases Editorial Board, are leaders in their fields and represent the full breadth of research on NTDs.

Open Access

PLOS applies the Creative Commons Attribution (CC BY) license to works we publish. This license was developed to facilitate open access – namely, free immediate access to, and unrestricted reuse of, original works of all types.

Under this license, authors agree to make articles legally available for reuse, without permission or fees, for virtually any purpose. Anyone may copy, distribute, or reuse these articles, as long as the author and original source are properly cited. Read more about our content license.

Measures of Impact

At PLOS, we believe that research articles should primarily be judged on their individual merits, rather than on the basis of the journal in which they were published. In March 2009, we inaugurated a program to provide Article-Level Metrics (ALM) on every article across all journals. Article-Level Metrics (ALMs) capture the manifold ways in which research is disseminated and can help users determine the value of an article to them and to their scientific community. Read more about Article-Level Metrics.

More Information


For more information about submitting to PLOS Neglected Tropical Diseases, read our checklist for getting started and our guidelines for preparing a submission.


Visit the Contact page for details about whom to contact with different queries.

Publication fees

PLOS Neglected Tropical Diseases publication fees are US$2250 per manuscript and will be billed upon acceptance. Authors’ ability to pay publication fees will never be a consideration in the decision whether to publish. Read more about publication fees and publication fee support.

About PLOS journals

PLOS publishes a suite of influential journals from all areas of science and medicine that contain rigorously reported, peer reviewed Open Access research articles. The journals vary in their criteria for publication and, with the exception of PLOS ONE, also publish a variety of influential and educational non-research content. The journals are editorially independent. Read more about the PLOS suite of journals.