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Are you ready to submit your manuscript? Please review the submission guidelines, guidelines for other article types, editorial and publishing policiesfigure guidelines, and table guidelines. Then, refer to this checklist to ensure that you have gathered all the relevant information and that the manuscript is formatted appropriately.

All manuscripts must be submitted in the online submission system.

  Refer to our sample files to ensure that your submission meets our formatting requirements.

If you are unsure whether your work satisfies the basic requirements for publication in PLOS Neglected Tropical Diseases, we are happy to consider a Presubmission Inquiry. For more information, read the Presubmission Inquiry guidelines

Submission Checklist

License agreement

Have you read the license agreement and are you able to sign it on behalf of all the authors?

Publication fees

Have you discussed the publication fees with your co-authors? Publication fees are US$2350 per manuscript and will be billed upon acceptance. Editors and reviewers have no access to payment information, therefore inability to pay does not influence the decision to publish a paper.

Group authors and consortia

If your author list includes a group author or consortium, enter its name in the free text box.


Specify whether your manuscript is currently posted on a preprint server. If so, provide the DOI or identifier.

If your submission describes primary research in the life sciences and has not already been posted as a preprint, you may opt-in to have it posted to the bioRxiv preprint server concurrent with your submission to PLOS Neglected Tropical Diseases.

If you choose to post your manuscript to bioRxiv, select the article category and subject from the dropdown lists provided.

Collection Submissions

If you were invited to submit your paper to a PLOS Special Collection, have you reviewed the terms of submission and publication charges for PLOS Special Collections, and are you prepared to adhere to them?

Cover letter

Have you prepared a cover letter explaining why you consider this manuscript suitable for publication in PLOS Neglected Tropical Diseases?


Does your paper fall into the scope of PLOS Neglected Tropical Diseases? If the disease in your paper is not listed in the scope, have you sent a Presubmission Inquiry to ask the editors whether the paper is suitable?

Author list

Are all authors aware of, and do they approve of, the submission of the manuscript, its content, authorship, and the order of authorship?

Do you have the following information for all authors?

The corresponding author must provide an ORCID iD at the time of submission by entering it in the user profile in the submission system. For more information about how to register for an ORCID iD and link it to Editorial Manager, watch this short video.


Have you prepared a statement indicating who funded the study, and the role of the funding agency in conducting the study and in preparing the manuscript? You will be asked to enter this into the relevant section of the submission form.

Human and animal research

If your article includes human or animal research, have you read and followed our policies on human subjects research and animal research, which contain further information on the Declaration of Helsinki and The use of non-human primates in research (PDF)?

For research involving vertebrates please note, as part of the ethics statement, the guidelines followed and the committee that approved of the methods employed.

Do you have a copy of the statement from the relevant institutional review board or ethics committee indicating their approval of the research reported in the manuscript which you can upload as supporting information?

If your submission contains content that could identify individual patients (such as photos, descriptions, pedigrees), we request that you provide copies of informed consent forms from those patients as supporting information. Have the patients been informed that under Open Access this published information can be used for any lawful purpose?


Have you confirmed that anyone named in the acknowledgments section agrees to being so named?

Clinical trials

If reporting a clinical trial have you provided the registration number, do you have a copy of the protocol that you can upload as supporting information, and are you reporting it according to the CONSORT guidelines? Have you completed and attached the CONSORT checklist?

Manuscript organization

Does your paper follow the organization guidelines outlined in the submission guidelines?

Systematic reviews

If your manuscript comprises a systematic review of randomized controlled trials, are you reporting it according to the PRISMA Guidelines? Have you included a PRISMA checklist and flow diagram?

Reporting guidelines

If the study describes a diagnostic technique, are you reporting it according to the STARD guidelines?

If reporting an epidemiological study are you reporting it according the STROBE requirements?

If your study includes microarray data, are you reporting it according to the MIAME guidelines and have you deposited the data in a public database?

Statistical methods

Have you included detailed descriptions of the statistical methods employed in your study and do you provide a measure of error in any data reported?


Have non-standard abbreviations been defined in the text?

Line numbers

Have you added line numbers to your manuscript?


Have you used standard nomenclature?

SI values

Have you used SI values?

File format

Is the manuscript file in DOC, DOCX, PDF, or RTF? If you prepared your article using LaTeX, please refer to our LaTeX guidelines for details about LaTeX files.


Have your original figures been created as EPS or TIFF files in a high enough resolution (300 ppi – 600 ppi) to provide for adequate review? Please note that individual files should not exceed 10 MB in size.

If your manuscript is ready for publication, do your figures conform to the figure guidelines

Related manuscripts

Are related manuscripts by any of the authors submitted or in press elsewhere? If so, are you prepared to provide PDFs as supporting information?

Suggested editors

Have you identified potential editors who would be qualified to handle your submission? See the full Editorial Board list for more information, being mindful of any potential competing interests

Suggested reviewers

Have you identified at least four potential reviewers whose email addresses you can provide? Please ensure that you are aware of our competing interests policy when making these suggestions, and do not suggest colleagues who may have any of these conflicts.

Other Article Type Submissions

Are you submitting a manuscript that is not a research article? Read the guidelines for other article types.

Revised Manuscripts

Are you submitting a revision? Read the guidelines for revised manuscripts.


Please contact if you have any questions.

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