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Open Access
Peer-reviewed
Research Article
Switching HIV Treatment in Adults Based on CD4 Count Versus Viral Load Monitoring: A Randomized, Non-Inferiority Trial in Thailand
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Gonzague Jourdain,
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Sophie Le Cœur,
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America, Unité Mixte de Recherche 196, Centre Français de la Population et du Développement, (INED-IRD-Paris V University), Paris, France
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Nicole Ngo-Giang-Huong,
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Patrinee Traisathit,
Affiliation Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
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Tim R. Cressey,
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Federica Fregonese,
Affiliation Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand
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Baptiste Leurent,
Affiliation Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand
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Intira J. Collins,
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Malee Techapornroong,
Affiliation Prapokklao Hospital, Ministry of Public Health, Chanthaburi, Thailand
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Sukit Banchongkit,
Affiliation Rayong Hospital, Ministry of Public Health, Rayong, Thailand
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Sudanee Buranabanjasatean,
Affiliation Mae Chan Hospital, Ministry of Public Health, Chiang Rai, Thailand
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Guttiga Halue,
Affiliation Phayao Provincial Hospital, Ministry of Public Health, Phayao, Thailand
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Ampaipith Nilmanat,
Affiliation Hat Yai Hospital, Ministry of Public Health, Songkla, Thailand
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Nuananong Luekamlung,
Affiliation Lamphun Hospital, Ministry of Public Health, Lamphun, Thailand
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Virat Klinbuayaem,
Affiliation Sanpatong Hospital, Ministry of Public Health, Chiang Mai, Thailand
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Apichat Chutanunta,
Affiliation Samutsakhon Hospital, Ministry of Public Health, Samutsakhon, Thailand
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Pacharee Kantipong,
Affiliation Chiangrai Prachanukroh Hospital, Ministry of Public Health, Chiang Rai, Thailand
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Chureeratana Bowonwatanuwong,
Affiliation Chonburi Hospital, Ministry of Public Health, Chonburi, Thailand
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Rittha Lertkoonalak,
Affiliation Maharat Nakhon Ratchasima Hospital, Ministry of Public Health, Nakhon Ratchasima, Thailand
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Prattana Leenasirimakul,
Affiliation Nakornping Hospital, Ministry of Public Health, Chiang Mai, Thailand
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Somboon Tansuphasawasdikul,
Affiliation Buddhachinaraj Hospital, Ministry of Public Health, Pitsanuloke, Thailand
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Pensiriwan Sang-a-gad,
Affiliation Ratchaburi Hospital, Ministry of Public Health, Ratchaburi, Thailand
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Panita Pathipvanich,
Affiliation Lampang Hospital, Ministry of Public Health, Lampang, Thailand
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Srisuda Thongbuaban,
Affiliation Mahasarakam Hospital, Ministry of Public Health, Mahasarakam, Thailand
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Pakorn Wittayapraparat,
Affiliation Bhuddasothorn Hospital, Ministry of Public Health, Chachoengsao, Thailand
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Naree Eiamsirikit,
Affiliation Samutprakarn Hospital, Ministry of Public Health, Samutprakarn, Thailand
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Yuwadee Buranawanitchakorn,
Affiliation Chiang Kham Hospital, Ministry of Public Health, Phayao, Thailand
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Naruepon Yutthakasemsunt,
Affiliation Nong Khai Hospital, Ministry of Public Health, Nong Khai, Thailand
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Narong Winiyakul,
Affiliation Regional Health Promotion Centre 6, Ministry of Public Health, Khon Kaen, Thailand
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Luc Decker,
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
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Sylvaine Barbier,
Affiliation Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand
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Suporn Koetsawang,
Affiliation Family Health Research Center, Mahidol University, Bangkok, Thailand
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Wasna Sirirungsi,
Affiliation Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
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Kenneth McIntosh,
Affiliations Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America, Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America
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Sombat Thanprasertsuk,
Affiliation Ministry of Public Health, Nonthaburi, Thailand
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Marc Lallemant ,
* E-mail: marc@phpt.org
Affiliations Unité Mixte Internationale 174, Institut de Recherche pour le Développement (IRD)-Programs for HIV Prevention and Treatment (PHPT), Chiang Mai, Thailand, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Switching HIV Treatment in Adults Based on CD4 Count Versus Viral Load Monitoring: A Randomized, Non-Inferiority Trial in Thailand
- Gonzague Jourdain,
- Sophie Le Cœur,
- Nicole Ngo-Giang-Huong,
- Patrinee Traisathit,
- Tim R. Cressey,
- Federica Fregonese,
- Baptiste Leurent,
- Intira J. Collins,
- Malee Techapornroong,
- Sukit Banchongkit
- Published: August 6, 2013
- https://doi.org/10.1371/journal.pmed.1001494