The Stardust protein is a key regulator of apical identity in polarized epithelia. Dynein-dependent apical localization of certain stardust mRNA isoforms may also play a functional role in apico-basal polarity regulation. The image shows the apical enrichment of stardust transcripts (green puncta) in the Drosophila follicle cell epithelium (see Horne-Badovinac and Bilder, e8).
Image Credit: Confocal micrograph provided by Sally Horne-Badovinac.
Perspective
Application of Ancestry Informative Markers to Association Studies in European Americans
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040005
Related Articles
Review
Exploration of Small RNAs
PLOS Genetics: published January 25, 2008 | https://doi.org/10.1371/journal.pgen.0040022
Research Articles
Discerning the Ancestry of European Americans in Genetic Association Studies
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0030236
Related Articles
Haplotype Mapping of a Diploid Non-Meiotic Organism Using Existing and Induced Aneuploidies
PLOS Genetics: published January 4, 2008 | https://doi.org/10.1371/journal.pgen.0040001
Dissecting the Genetic Components of Adaptation of Escherichia coli to the Mouse Gut
PLOS Genetics: published January 11, 2008 | https://doi.org/10.1371/journal.pgen.0040002
Repetitive Element-Mediated Recombination as a Mechanism for New Gene Origination in Drosophila
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040003
Analysis and Application of European Genetic Substructure Using 300 K SNP Information
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040004
Related Articles
The Molecular Mechanisms of OPA1-Mediated Optic Atrophy in Drosophila Model and Prospects for Antioxidant Treatment
PLOS Genetics: published January 11, 2008 | https://doi.org/10.1371/journal.pgen.0040006
Dynein Regulates Epithelial Polarity and the Apical Localization of stardust A mRNA
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040008
Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040009
TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040010
Protein Under-Wrapping Causes Dosage Sensitivity and Decreases Gene Duplicability
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040011
Related Articles
Dominant-Negative CK2α Induces Potent Effects on Circadian Rhythmicity
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040012
Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9
PLOS Genetics: published January 25, 2008 | https://doi.org/10.1371/journal.pgen.0040013
Molecular Landscape of Modified Histones in Drosophila Heterochromatic Genes and Euchromatin-Heterochromatin Transition Zones
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040016
Nuc2p, a Subunit of the Anaphase-Promoting Complex, Inhibits Septation Initiation Network Following Cytokinesis in Fission Yeast
PLOS Genetics: published January 25, 2008 | https://doi.org/10.1371/journal.pgen.0040017
The Genetic Structure of Pacific Islanders
PLOS Genetics: published January 18, 2008 | https://doi.org/10.1371/journal.pgen.0040019
Related Articles
Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein
PLOS Genetics: published January 25, 2008 | https://doi.org/10.1371/journal.pgen.0040021
Correction
Correction: A Hybrid Photoreceptor Expressing Both Rod and Cone Genes in a Mouse Model of Enhanced S-Cone Syndrome
PLOS Genetics: published January 25, 2008 | https://doi.org/10.1371/journal.pgen.0040018