Delta family protocadherins contribute to protoglomerular targeting of olfactory sensory neuron axons in the olfactory bulb

Daniel T. Barnes, Ezekiel M. D. Crenshaw, Matthew J. Curran, Jessica B. Herr, Emily S. Devereaux, Carly D. Seligman, Jonathan A. Raper

PLOS Genetics: published April 1, 2026 | https://doi.org/10.1371/journal.pgen.1012090

The geometry of G × E: How scaling and endogenous treatment effects shape interaction direction

Michal Sadowski, Andy W. Dahl, Noah Zaitlen, Richard Border

PLOS Genetics: published April 1, 2026 | https://doi.org/10.1371/journal.pgen.1012073

ADNP regulates chromatin architecture and lineage fidelity during neural differentiation

Phillip Wulfridge, Nathaniel Rell, John Doherty, Kuo-Chen Fang, Michelle Lee Lynskey, Kavitha Sarma

PLOS Genetics: published April 1, 2026 | https://doi.org/10.1371/journal.pgen.1012081

DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A

Ioannis Kafetzopoulos, Francesca Taglini, Moira Pasquier, Hazel Davidson-Smith, Christine J. Rodger, Lucia Puchades Gimeno, Andrew A. Malcolm, Duncan Sproul

PLOS Genetics: published April 2, 2026 | https://doi.org/10.1371/journal.pgen.1012098

System drift in the evolution of plant meristem development

Pjotr L. van der Jagt, Steven Oud, Renske M. A. Vroomans

PLOS Genetics: published April 3, 2026 | https://doi.org/10.1371/journal.pgen.1012089

Translation control by altered start codon usage as a means of modulating the general stress response and virulence in Listeria monocytogenes

Jialun Wu, Claire Kelly, Duarte N. Guerreiro, Brenda Chanza, Ashley Reade, Catherine M. Burgess, Conor O’Byrne

PLOS Genetics: published April 6, 2026 | https://doi.org/10.1371/journal.pgen.1011851

Establishment of a congenic strain for the oyster mushroom reveals the structure and evolution of mating-type loci

Yi-Yun Lee, Guillermo Vidal-Diez de Ulzurrun, Rebecca J. Tay, Yen-Ping Hsueh

PLOS Genetics: published April 8, 2026 | https://doi.org/10.1371/journal.pgen.1011966

Lactate and histone H3K18 lactylation are associated with metabolic control of gene expression in the retina

Mohita Gaur, Matthew J. Brooks, Xulong Liang, Ke Jiang, Anjani Kumari, Milton A. English, Paolo Cifani, Maria C. Panepinto, Jacob Nellissery, Robert N. Fariss, Laura Campello, Claire Marchal, Anand Swaroop

PLOS Genetics: published April 8, 2026 | https://doi.org/10.1371/journal.pgen.1012100

ZmSKIP enhances drought tolerance by reducing stomatal aperture in maize

Yao Wang, Yujiao Zhou, Qimeng Li, Yanyan Zhang, Li Yang, Qiao Zhou, Wen Xu, Tianhong Liu, Yaxi Liu, Fengkai Wu, Guangchao Sun, Wei Guo, Yanli Lu, Jie Xu

PLOS Genetics: published April 13, 2026 | https://doi.org/10.1371/journal.pgen.1012077

Chronic replication stress-mediated genomic instability disrupts placenta development in mice

Mumingjiang Munisha, Rui Huang, Jordan Khan, John C. Schimenti

PLOS Genetics: published April 13, 2026 | https://doi.org/10.1371/journal.pgen.1012111

Oocyte vitrification disrupts zygotic genome activation in embryos by impairing maternal spliceosome translation and Crxos splicing

Jianpeng Qin, Ao Ning, Jian Han, Xiangyi Chen, Beijia Cao, Yujun Yao, Xiaoqing He, Bo Pan, Yaozong Wei, Kunlin Du, Shuqi Zou, Jiangfeng Ye, Guozhi Yu, Qiuxia Liang, Jie Qiao, Jie Yan, Guangbin Zhou

PLOS Genetics: published April 15, 2026 | https://doi.org/10.1371/journal.pgen.1012121

Worm orthologues of cytokinesis-associated proteins CIT and ASPM regulate neuronal microtubule dynamics and polarity in C. elegans

Sunanda Sharma, Keerthana Ponniah, Ishanee Bandyopadhyay, Devyani Vadawale, Sandhya P. Koushika, Anindya Ghosh-Roy

PLOS Genetics: published April 15, 2026 | https://doi.org/10.1371/journal.pgen.1012106

Constitutively active RAS prolongs Cdc42 signalling, while MAPK signalling is attenuated during fission yeast mating

Emma J. Kelsall, Akatsuki Kimura, Ábel Vértesy, Kornelis R. Straatman, Mishal Tariq, Raquel Gadea, Chandni Parmar, Gabriele Schreiber, Shubhchintan Randhawa, Takashi Y. Ida, Cyril Dominguez, Edda Klipp, Kayoko Tanaka

PLOS Genetics: published April 17, 2026 | https://doi.org/10.1371/journal.pgen.1012117

Whole-genome sequencing reveals a possible molecular basis of sex determination in the dioecious wild yam Dioscorea tokoro

Aoi Kudoh, Satoshi Natsume, Yu Sugihara, Hiroaki Kato, Akira Abe, Kaori Oikawa, Motoki Shimizu, Kazue Itoh, Mai Tsujimura, Yoshitaka Takano, Toshiyuki Sakai, Hiroaki Adachi, Atsushi Ohta, Mina Ohtsu, Takuma Ishizaki, Toru Terachi, Hideki Innan, Ryohei Terauchi

PLOS Genetics: published April 20, 2026 | https://doi.org/10.1371/journal.pgen.1012123

Examining the association between fetal HLA-C, maternal KIR haplotypes and birth weight

Caitlin Stephanie Decina, Nicole M. Warrington, Robin N. Beaumont, Beilei Bian, Caroline Brito Nunes, Geng Wang, William L. Lowe Jr, David Squire, Damjan Vukcevic, Stephen Leslie, Rachel M. Freathy, David M. Evans

PLOS Genetics: published April 20, 2026 | https://doi.org/10.1371/journal.pgen.1012102

Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways

Rita A. Batista, Eléonore Durand, Monika Mörchen, Jacinthe Azevedo-Favory, Samson Simon, Manu Dubin, Vinod Kumar, Eléanore Lacoste, Corinne Cruaud, Christelle Blassiau, Matteo Barois, Anne-Catherine Holl, Chloé Ponitzki, Nathalie Faure, William Marande, Sonia Vautrin, Isabelle Fobis-Loisy, Jean-Marc Aury, Sylvain Legrand, Ute Krämer, Thierry Lagrange, Xavier Vekemans, Vincent Castric

PLOS Genetics: published April 20, 2026 | https://doi.org/10.1371/journal.pgen.1012127

Epigenetic gene regulation is controlled by distinct regulatory complexes utilizing specialized paralogs of TELOMERE REPEAT BINDING FACTORS

Maik Mendler, Kristin Krause, Simone Zündorf, Prathamesh Sannak, Petra Tänzler, Sara Stolze, Hirofumi Nakagami, Franziska Turck

PLOS Genetics: published April 21, 2026 | https://doi.org/10.1371/journal.pgen.1012114

Inducible gene deletion reveals essentiality of protein kinases and a septation initiation network in Candida albicans

Bernardo Ramírez-Zavala, Ines Krüger, Sonja Schwanfelder, Johannes Lackner, Thomas Krüger, Olaf Kniemeyer, Joachim Morschhäuser

PLOS Genetics: published April 21, 2026 | https://doi.org/10.1371/journal.pgen.1012118

The transcription factor TaWRKY58 coordinates growth and drought sensitivity in wheat by repressing TaLRR and TaBCS1

Yazhou Zhang, Xinyao Cheng, Xinyu Yu, Anyu Gu, Xufei Zhao, Mei Deng, Guoyue Cheng, Qiang Xu, Qiantao Jiang, Yuming Wei

PLOS Genetics: published April 24, 2026 | https://doi.org/10.1371/journal.pgen.1012124

Nebivolol suppresses glioblastoma progression via dual modulation of mitochondrial metabolism and AKT/mTOR/4EBP1 signaling axis

Lingni Zhou, Hongyu Che, Hongyan Jiang, Luxin Yin, Yongang Jiang, Yuhui Zhang, Haoran Liang, Rutong Yu, Xu Zhang, Xuejiao Liu

PLOS Genetics: published April 24, 2026 | https://doi.org/10.1371/journal.pgen.1012120

The pos-1 3′ untranslated region governs germline specification and proliferation to ensure reproductive robustness

Haik V. Varderesian, Juliet N. Utaegbulam, Hannah E. Brown, Beverly Ramirez, Melina Velcani, Sean P. Ryder

PLOS Genetics: published April 27, 2026 | https://doi.org/10.1371/journal.pgen.1012129

Potential Rad54 separation of function mutation highlights unique roles during homologous recombination

Jingyi Hu, David Moraga, Amanda Xu, Lauren Peysakhova, J. Brooks Crickard

PLOS Genetics: published April 27, 2026 | https://doi.org/10.1371/journal.pgen.1012136

A positive feedback loop between sensory and octopaminergic neurons underlies nociceptive plasticity in Drosophila larvae

Jean-Christophe Boivin, Yi Q. Zhao, Jiayi Zhu, Jared T. Dakin, Jing Ning, Tomoko Ohyama

PLOS Genetics: published April 28, 2026 | https://doi.org/10.1371/journal.pgen.1012122

The RCAR12-CAP1-OST1 module controls ABA-mediated stomatal closure in Arabidopsis

Xiaoyi Li, Qian Zhang, Jiangjie Kang, Lianxin Jiang, Yihan Feng, Juan Du, Chaowen Xiao, Jianglan Wei, Qirong Wen, Ying Wang, Jianmei Wang, Yi Yang

PLOS Genetics: published April 28, 2026 | https://doi.org/10.1371/journal.pgen.1012092

INS-17 acts as a nutrient deprivation signal to mediate adult IIS-regulated associative behaviors in C. elegans

Emily J. Leptich, Priyadharshini Vijayakumar, Edward W. Pietryk, Meredith I. Williams, Rachana Rajupalem, Rachel N. Arey

PLOS Genetics: published April 28, 2026 | https://doi.org/10.1371/journal.pgen.1012130

A novel role of tRNA-derived fragments in porcine granulosa-oocyte cell communication and cuproptosis

Linyuan Shen, Xue Zhao, Shuang Wu, Yuhang Lei, Shuang Liang, Saihao Wang, Haodong Dai, Yan Wang, Lei Chen, Ye Zhao, Mailin Gan, Shijun Xiao, Guangbin Zhou, Li Zhu

PLOS Genetics: published April 30, 2026 | https://doi.org/10.1371/journal.pgen.1012119

Correction: An essential gene screening identifies yeast Mot1 as a suppressor of R-loops and genome instability

María E. Soler-Oliva, Rocío A. Domínguez-Sierra, Hélène Gaillard, Andrés Aguilera

PLOS Genetics: published April 10, 2026 | https://doi.org/10.1371/journal.pgen.1012108

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Correction: Transcriptional repression of reaper by Stand still ensures female germline development in Drosophila

The PLOS Genetics Staff

PLOS Genetics: published April 15, 2026 | https://doi.org/10.1371/journal.pgen.1012116

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Correction: Regulatory rewiring drives intraspecies competition in Bacillus subtilis

Margarita Kalamara, Alistair Bonsall, Jonathan Griffin, Joana Carneiro, Marek Gierlinski, Lukas Eigentler, David Stevenson, Amy Wood, Michael Porter, Helge C. Dorfmueller, Cait E. MacPhee, James C. Abbott, Nicola R. Stanley-Wall

PLOS Genetics: published April 21, 2026 | https://doi.org/10.1371/journal.pgen.1012128

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Correction: Functional redundancy and formin-isoform independent localization of tropomyosin paralogs in Saccharomyces cerevisiae

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PLOS Genetics: published April 28, 2026 | https://doi.org/10.1371/journal.pgen.1012065

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