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Open Access
Peer-reviewed
Research Article
Functional Polymorphisms in PRODH Are Associated with Risk and Protection for Schizophrenia and Fronto-Striatal Structure and Function
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Lucas Kempf,
Affiliations Unit of Systems Neuroscience in Psychiatry, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Kristin K. Nicodemus,
Current address: Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Bhaskar Kolachana,
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Radhakrishna Vakkalanka,
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Beth A. Verchinski,
Affiliations Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Neuroimaging Core Facility, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Michael F. Egan,
Current address: Merck & Co, Inc., West Point, Pennsylvania, United States of America
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Richard E. Straub,
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Venkata A. Mattay,
Affiliations Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Neuroimaging Core Facility, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Joseph H. Callicott,
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Daniel R. Weinberger ,
* E-mail: weinberd@mail.nih.gov (DRW); a.meyer-lindenberg@zi-mannheim.de (AML)
Affiliation Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America
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Andreas Meyer-Lindenberg
* E-mail: weinberd@mail.nih.gov (DRW); a.meyer-lindenberg@zi-mannheim.de (AML)
Affiliations Unit of Systems Neuroscience in Psychiatry, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Neuroimaging Core Facility, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Central Institute of Mental Health, Mannheim, Germany
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Functional Polymorphisms in PRODH Are Associated with Risk and Protection for Schizophrenia and Fronto-Striatal Structure and Function
- Lucas Kempf,
- Kristin K. Nicodemus,
- Bhaskar Kolachana,
- Radhakrishna Vakkalanka,
- Beth A. Verchinski,
- Michael F. Egan,
- Richard E. Straub,
- Venkata A. Mattay,
- Joseph H. Callicott,
- Daniel R. Weinberger
- Published: November 7, 2008
- https://doi.org/10.1371/journal.pgen.1000252