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Review

A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker

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This article outlines the broad features of the various quantitative trait transmission/disequilibrium test procedures carried out in the frequently used QTDT and FBAT packages.

 

Featured Research

Mutation and Evolutionary Rates in Adélie Penguins from the Antarctic

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The authors present data on the rate of mutation of the mitochondrial hypervariable region in Adélie penguins from the Antarctic and compare this to the rate of evolution estimated using serially preserved ancient remains.

 

Time-Lapse Analysis and Mathematical Characterization Elucidate Novel Mechanisms Underlying Muscle Morphogenesis

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Although adhesion to laminin has been implicated in muscular dystrophies where the attachment between muscle cells and tendons fails, no early developmental requirements for laminin in fast muscle morphogenesis have been shown until now.

 

Mutability and Importance of a Hypermutable Cell Subpopulation that Produces Stress-Induced Mutants in Escherichia coli

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These findings support the hypothesis that the hypermutable cell subpopulation underlies most stress-induced mutants, rather than a minority of them.

 

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