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Open Access
Peer-reviewed
Research Article
Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation
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Masashi Miguchi,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Takao Hinoi ,
* E-mail: thinoi@hiroshima-u.ac.jp
Affiliations Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Department of Surgery, Institute for Clinical Research, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan
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Manabu Shimomura,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Tomohiro Adachi,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Yasufumi Saito,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Hiroaki Niitsu,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Masatoshi Kochi,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Haruki Sada,
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Yusuke Sotomaru,
Affiliation Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan
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Tsuneo Ikenoue,
Affiliation Division of Clinical Genome Research, the Institute of Medical Science, University of Tokyo, Tokyo, Japan
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Kunitoshi Shigeyasu,
Affiliation Department of Surgery, National Hospital Organization Iwakuni Clinical Center, Yamaguchi, Japan
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Kohji Tanakaya,
Affiliation Department of Surgery, National Hospital Organization Iwakuni Clinical Center, Yamaguchi, Japan
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Yasuhiko Kitadai,
Affiliations Departments of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Department of Health Science, Program in Human Culture and Science, Prefectural University of Hiroshima, Hiroshima, Japan
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Kazuhiro Sentani,
Affiliation Department of Molecular Pathology, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Naohide Oue,
Affiliation Department of Molecular Pathology, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Wataru Yasui,
Affiliation Department of Molecular Pathology, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Hideki Ohdan
Affiliation Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan
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Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation
- Masashi Miguchi,
- Takao Hinoi,
- Manabu Shimomura,
- Tomohiro Adachi,
- Yasufumi Saito,
- Hiroaki Niitsu,
- Masatoshi Kochi,
- Haruki Sada,
- Yusuke Sotomaru,
- Tsuneo Ikenoue
- Published: November 11, 2016
- https://doi.org/10.1371/journal.pone.0166422