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Open Access
Peer-reviewed
Research Article
Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status
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Timothy M. LeJeune ,
Contributed equally to this work with: Timothy M. LeJeune, Hei Yin Tsui
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Hei Yin Tsui ,
Contributed equally to this work with: Timothy M. LeJeune, Hei Yin Tsui
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Laura B. Parsons,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Gerald E. Miller,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Crystal Whitted,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Kayla E. Lynch,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Robert E. Ramsauer,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Jasmine U. Patel,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Jarrett E. Wyatt,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Doris S. Street,
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Carolyn B. Adams ,
¶‡ These authors also contributed equally to this work.
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Brian McPherson ,
¶‡ These authors also contributed equally to this work.
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Hei Man Tsui ,
¶‡ These authors also contributed equally to this work.
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Julie A. Evans ,
¶‡ These authors also contributed equally to this work.
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Christopher Livesay ,
¶‡ These authors also contributed equally to this work.
Affiliation Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Ruben D. Torrenegra,
Affiliation Universidad de Ciencias Aplicadas y Ambientales, Bogota, Colombia
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Victoria E. Palau
* E-mail: palauv@etsu.edu
Affiliations Division of Hematology-Oncology, Department of Internal Medicine, James Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, United States of America, Department of Pharmaceutical Sciences, Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, United States of America
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Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status
- Timothy M. LeJeune,
- Hei Yin Tsui,
- Laura B. Parsons,
- Gerald E. Miller,
- Crystal Whitted,
- Kayla E. Lynch,
- Robert E. Ramsauer,
- Jasmine U. Patel,
- Jarrett E. Wyatt,
- Doris S. Street
- Published: November 25, 2015
- https://doi.org/10.1371/journal.pone.0142928