The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors

Laura E. Newman; Cara R. Schiavon; Chengjing Zhou; Richard A. Kahn

doi:10.1371/journal.pone.0175164

Loading metrics

Open Access

Peer-reviewed

Research Article

The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors

Laura E. Newman ,

Contributed equally to this work with: Laura E. Newman, Cara R. Schiavon

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Cara R. Schiavon ,

Contributed equally to this work with: Laura E. Newman, Cara R. Schiavon

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Chengjing Zhou,

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Richard A. Kahn

* E-mail: rkahn@emory.edu

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯

The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors

Laura E. Newman,
Cara R. Schiavon,
Chengjing Zhou,
Richard A. Kahn

Published: April 5, 2017
https://doi.org/10.1371/journal.pone.0175164

About the Authors

Laura E. Newman

Contributed equally to this work with: Laura E. Newman, Cara R. Schiavon

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

Cara R. Schiavon

Contributed equally to this work with: Laura E. Newman, Cara R. Schiavon

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

Chengjing Zhou

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

Richard A. Kahn

* E-mail: rkahn@emory.edu

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: LEN CRS RAK. Data curation: LEN CRS CZ. Formal analysis: LEN CRS. Funding acquisition: LEN RAK. Investigation: LEN CRS CZ. Project administration: RAK. Resources: RAK. Supervision: RAK. Validation: LEN CRS. Visualization: LEN CRS. Writing – original draft: LEN CRS RAK. Writing – review & editing: LEN CRS RAK.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Cell fusion
Is the Subject Area "Cell fusion" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Guanosine triphosphatase
Is the Subject Area "Guanosine triphosphatase" applicable to this article?

Thanks for your feedback.
Immunoblotting
Is the Subject Area "Immunoblotting" applicable to this article?

Thanks for your feedback.
Cellular stress responses
Is the Subject Area "Cellular stress responses" applicable to this article?

Thanks for your feedback.