About the Authors

Joanna F. Dipnall

jdipnall@deakin.edu.au

Affiliations IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia, Department of Statistics, Data Science and Epidemiology, Swinburne University of Technology, Melbourne, Victoria, Australia

Julie A. Pasco

Contributed equally to this work with: Julie A. Pasco, Michael Berk, Lana J. Williams, Seetal Dodd, Felice N. Jacka, Denny Meyer

Affiliations IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia, Melbourne Clinical School-Western Campus, The University of Melbourne, St Albans, VIC, Australia, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia, University Hospital Geelong, Geelong VIC Australia

Michael Berk

Contributed equally to this work with: Julie A. Pasco, Michael Berk, Lana J. Williams, Seetal Dodd, Felice N. Jacka, Denny Meyer

Affiliations IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia, University Hospital Geelong, Geelong VIC Australia, Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia, Orygen, the National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia

Lana J. Williams

Contributed equally to this work with: Julie A. Pasco, Michael Berk, Lana J. Williams, Seetal Dodd, Felice N. Jacka, Denny Meyer

Affiliations IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia, University Hospital Geelong, Geelong VIC Australia

Seetal Dodd

Contributed equally to this work with: Julie A. Pasco, Michael Berk, Lana J. Williams, Seetal Dodd, Felice N. Jacka, Denny Meyer

Affiliations IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia, University Hospital Geelong, Geelong VIC Australia, Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia, Orygen, the National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia

Felice N. Jacka

Contributed equally to this work with: Julie A. Pasco, Michael Berk, Lana J. Williams, Seetal Dodd, Felice N. Jacka, Denny Meyer

Affiliations IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia, Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia, Centre for Adolescent Health, Murdoch Children’s Research Institute, Melbourne, Australia, Black Dog Institute, Sydney, Australia

Denny Meyer

Contributed equally to this work with: Julie A. Pasco, Michael Berk, Lana J. Williams, Seetal Dodd, Felice N. Jacka, Denny Meyer

Affiliation Department of Statistics, Data Science and Epidemiology, Swinburne University of Technology, Melbourne, Victoria, Australia

Competing Interests

JFD has no conflicts of interest in relation to this manuscript. JAP has recently received grant/research support from the National Health and Medical Research Council (NHMRC), BUPA Foundation, Amgen,/GlaxoSmithKline/Osteoporosis Australia/Australian and New Zealand Bone and Mineral Society, Western Alliance, Barwon Health, Deakin University and the Geelong Community Foundation. MB has received Grant/Research Support from the NIH, Cooperative Research Centre, Simons Autism Foundation, Cancer Council of Victoria, Stanley Medical Research Foundation, MBF, NHMRC, Beyond Blue, Rotary Health, Geelong Medical Research Foundation, Bristol Myers Squibb, Eli Lilly, Glaxo SmithKline, Meat and Livestock Board, Organon, Novartis, Mayne Pharma, Servier and Woolworths, has been a speaker for Astra Zeneca, Bristol Myers Squibb, Eli Lilly, Glaxo SmithKline, Janssen Cilag, Lundbeck, Merck, Pfizer, Sanofi Synthelabo, Servier, Solvay and Wyeth, and served as a consultant to Astra Zeneca, Bioadvantex, Bristol Myers Squibb, Eli Lilly, Glaxo SmithKline, Janssen Cilag, Lundbeck Merck and Servier. Drs Copolov, MB and Bush are co-inventors of provisional patent 02799377.3-2107-AU02 “Modulation of physiological process and agents useful for same”. MB and Laupu are co-authors of provisional patent 2014900627 “Modulation of diseases of the central nervous system and related disorders”. MB is supported by a NHMRC Senior Principal Research Fellowship 1059660. LJW is supported by a NHMRC Career Development Fellowship 1064272. SD has received grants/research support from the Stanley Medical Research Institute, NHMRC, Beyond Blue, ARHRF, Simons Foundation, Geelong Medical Research Foundation, Fondation FondaMental, Eli Lilly, Glaxo SmithKline, Organon, Mayne Pharma and Servier, speaker’s fees from Eli Lilly, advisory board fees from Eli Lilly and Novartis, and conference travel support from Servier. FNJ has received Grant/Research support from the Brain and Behaviour Research Institute, the National Health and Medical Research Council (NHMRC), Australian Rotary Health, the Geelong Medical Research Foundation, the Ian Potter Foundation, Eli Lilly, the Meat and Livestock Board and The University of Melbourne and has received speakers honoraria from Sanofi-Synthelabo, Janssen Cilag, Servier, Pfizer, Health Ed, Network Nutrition, Angelini Farmaceutica, and Eli Lilly. She is supported by an NHMRC Career Development Fellowship (#1108125). DM has received grant/research support from the Australian research Council (ARC), Mental Illness Research Fund (MIRF), Victorian Department of Justice, Beyond Blue, Swinburne University of Technology, Federal University. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: JFD. Formal analysis: JFD. Methodology: JFD DM. Software: JFD. Visualization: JFD. Writing – original draft: JFD. Writing – review & editing: JFD JAP MB LJW SD FNJ DM.