About the Authors

Amit K. Pandey

Affiliations Department of Medicine, University of California San Diego, San Diego, CA, United States of America, Department of Medicine, VA San Diego Healthcare System, San Diego, CA, United States of America

William F. Penny

Affiliations Department of Medicine, University of California San Diego, San Diego, CA, United States of America, Department of Medicine, VA San Diego Healthcare System, San Diego, CA, United States of America

Valmik Bhargava

Affiliations Department of Medicine, University of California San Diego, San Diego, CA, United States of America, Department of Medicine, VA San Diego Healthcare System, San Diego, CA, United States of America

N. Chin Lai

Affiliations Department of Medicine, University of California San Diego, San Diego, CA, United States of America, Department of Medicine, VA San Diego Healthcare System, San Diego, CA, United States of America

Ronghui Xu

Affiliations Department of Family Medicine and Public Health, University of California San Diego, San Diego, CA, United States of America, Department of Mathematics, University of California San Diego, San Diego, CA, United States of America

H. Kirk Hammond

khammond@ucsd.edu

Affiliations Department of Medicine, University of California San Diego, San Diego, CA, United States of America, Department of Medicine, VA San Diego Healthcare System, San Diego, CA, United States of America

Competing Interests

Dr. Hammond is founder, unpaid consultant, and equity holder of Renova Therapeutics. Renova did not fund the work and was not involved in its planning, interpretation or writing. None of the other authors have disclosures. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AKP HKH. Performed the experiments: WFP VB NCL HKH. Analyzed the data: AKP RX. Wrote the paper: AKP WFP VB NCL RX HKH.