About the Authors

Hossein Noyan

Contributed equally to this work with: Hossein Noyan, Omar El-Mounayri

Affiliation Division of Experimental Therapeutics, Toronto General Research Institute, Toronto, Ontario, Canada

Omar El-Mounayri

Contributed equally to this work with: Hossein Noyan, Omar El-Mounayri

Affiliation Division of Experimental Therapeutics, Toronto General Research Institute, Toronto, Ontario, Canada

Ruth Isserlin

Affiliation Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Sara Arab

Affiliation Division of Experimental Therapeutics, Toronto General Research Institute, Toronto, Ontario, Canada

Abdul Momen

Affiliation Division of Experimental Therapeutics, Toronto General Research Institute, Toronto, Ontario, Canada

Henry S. Cheng

Affiliation Division of Advanced Diagnostics, Toronto General Research Institute, Toronto, Ontario Canada

Jun Wu

Affiliation Division of Advanced Diagnostics, Toronto General Research Institute, Toronto, Ontario Canada

Talat Afroze

Affiliation Division of Experimental Therapeutics, Toronto General Research Institute, Toronto, Ontario, Canada

Ren-Ke Li

Affiliations Division of Advanced Diagnostics, Toronto General Research Institute, Toronto, Ontario Canada, Heart and Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, University of Toronto, Toronto, Ontario, Canada, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada

Jason E. Fish

Affiliations Division of Advanced Diagnostics, Toronto General Research Institute, Toronto, Ontario Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada, Heart and Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, University of Toronto, Toronto, Ontario, Canada, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada

Gary D. Bader

Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

Mansoor Husain

mansoor.husain@uhn.ca

Affiliations Division of Experimental Therapeutics, Toronto General Research Institute, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada, Heart and Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, University of Toronto, Toronto, Ontario, Canada, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Ted Rogers Centre for Heart Research, University Health Network, Toronto, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HN OE MH. Performed the experiments: HN OE AM HSC JW. Analyzed the data: HN OE RI HSC TA JW SA GDB JF MH. Contributed reagents/materials/analysis tools: JF GDB MH. Wrote the paper: HN OE TA JF GDB RKL MH.