About the Authors

Catherine Labbé

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Kotaro Ogaki

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Oswaldo Lorenzo-Betancor

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Minerva M. Carrasquillo

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Michael G. Heckman

Affiliation Section of Biostatistics, Mayo Clinic, Jacksonville, Florida, United States of America

Allan McCarthy

Affiliation Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland

Alexandra I. Soto-Ortolaza

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Ronald L. Walton

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Timothy Lynch

Affiliation Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland

Joanna Siuda

Affiliation Department of Neurology, Medical University of Silesia, Katowice, Poland

Grzegorz Opala

Affiliation Department of Neurology, Medical University of Silesia, Katowice, Poland

Anna Krygowska-Wajs

Affiliation Department of Neurology, Jagiellonian University, Krakow, Poland

Maria Barcikowska

Affiliation Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland

Krzysztof Czyzewski

Affiliation Department of Neurology, Central Hospital of the Ministry of Interior and Administration, Warsaw, Poland

Dennis W. Dickson

Affiliations Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America, Department of Pathology, Mayo Clinic, Jacksonville, Florida, United States of America

Ryan J. Uitti

Affiliation Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America

Zbigniew K. Wszolek

Affiliation Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America

Owen A. Ross

ross.owen@mayo.edu

Affiliation Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

Competing Interests

OAR, Ph.D., is a PLOS ONE Editorial Board member; this does not alter the authors' adherence to PLOS ONE editorial policies and criteria.

Author Contributions

Conceived and designed the experiments: CL OAR. Performed the experiments: CL KO OLB MMC MGH AM AISO RLW. Analyzed the data: CL KO OLB MMC MGH OAR. Contributed reagents/materials/analysis tools: MMC MGH TL JS GO AKW MB KC DWD RJU ZKW OAR. Wrote the paper: CL KO OLB MMC MGH AM AISO RLW TL JS GO AKW MB KC DWD RJU ZKW OAR.