About the Authors

Janice L. Farlow

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Hai Lin

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Laura Sauerbeck

Affiliation Department of Neurology and Rehabilitation Medicine, University of Cincinnati School of Medicine, Cincinnati, Ohio, United States of America

Dongbing Lai

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Daniel L. Koller

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Elizabeth Pugh

Affiliation Center for Inherited Disease Research, Johns Hopkins University; Baltimore, Maryland, United States of America

Kurt Hetrick

Affiliation Center for Inherited Disease Research, Johns Hopkins University; Baltimore, Maryland, United States of America

Hua Ling

Affiliation Center for Inherited Disease Research, Johns Hopkins University; Baltimore, Maryland, United States of America

Rachel Kleinloog

Affiliation Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

Pieter van der Vlies

Affiliation Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Patrick Deelen

Affiliations Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Morris A. Swertz

Affiliations Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Bon H. Verweij

Affiliation Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

Luca Regli

Affiliations Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland

Gabriel J. E. Rinkel

Affiliation Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

Ynte M. Ruigrok

Affiliation Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

Kimberly Doheny

Affiliation Center for Inherited Disease Research, Johns Hopkins University; Baltimore, Maryland, United States of America

Yunlong Liu

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Joseph Broderick

Affiliation Department of Neurology and Rehabilitation Medicine, University of Cincinnati School of Medicine, Cincinnati, Ohio, United States of America

Tatiana Foroud

tforoud@iu.edu

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

FIA Study Investigators

Membership of the FIA Study Investigators is provided in the Acknowledgements.

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JLF TF JB YL YMR. Performed the experiments: JL HL DL DLK EP KH HL KD. Analyzed the data: JLF TF JB EP KH HL KD RK PVDV PD MAS BHV LR GJER YMR. Contributed reagents/materials/analysis tools: JLF HL KH HL LS JB DL DLK. Wrote the paper: JLF TF EP KH HL KD JB YMR.