About the Authors
- Hannah Lees
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Affiliation Section of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom
- Jonathan Swann
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Affiliation Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading, United Kingdom
- Simon M. Poucher
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Current address: CrystecPharma, Crystec Ltd, Bradford, United Kingdom
Affiliation Cardiovascular and Gastro-Intestinal Disorders Innovative Medicines, AstraZeneca Pharmaceuticals, Alderley Park, Cheshire, United Kingdom
- Jeremy K. Nicholson
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Affiliation Section of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom
- Elaine Holmes
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Affiliation Section of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom
- Ian D. Wilson
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Affiliation Section of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom
- Julian R. Marchesi
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* E-mail: MarchesiJR@cardiff.ac.uk
Affiliations School of Biosciences, Cardiff University, Cardiff, United Kingdom, Centre for Digestive and Gut Health, Imperial College London, London, United Kingdom
Competing Interests
The authors have read the journal's policy and have the following conflicts: SMP and IDW were employees of AstraZeneca, the funder of this study, at the time of this study. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: IDW. Performed the experiments: HL. Analyzed the data: HL JRM. Contributed reagents/materials/analysis tools: IDW SMP. Wrote the paper: HL JS SMP JKN EH IDW JRM.