Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology

Marcio Luis Acencio; Luiz Augusto Bovolenta; Esther Camilo; Ney Lemke

doi:10.1371/journal.pone.0077521

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Open Access

Peer-reviewed

Research Article

Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology

Marcio Luis Acencio ,

* E-mail: mlacencio@ibb.unesp.br

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil
⨯
Luiz Augusto Bovolenta,

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil
⨯
Esther Camilo,

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil
⨯
Ney Lemke

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil
⨯

Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology

Marcio Luis Acencio,
Luiz Augusto Bovolenta,
Esther Camilo,
Ney Lemke

Published: October 25, 2013
https://doi.org/10.1371/journal.pone.0077521

About the Authors

Marcio Luis Acencio

* E-mail: mlacencio@ibb.unesp.br

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil

Luiz Augusto Bovolenta

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil

Esther Camilo

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil

Ney Lemke

Affiliation Department of Physics and Biophysics, Botucatu Biosciences Institute, UNESP – Univ Estadual Paulista, Botucatu, São Paulo, Brazil

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MLA NL. Performed the experiments: MLA. Analyzed the data: MLA. Contributed reagents/materials/analysis tools: LAB EC. Wrote the paper: MLA NL.

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Oncogenic signaling
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Carcinogenesis
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Cancers and neoplasms
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Forecasting
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Protein interactions
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Centrality
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Protein interaction networks
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Drug interactions
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