TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

Crystal L. Jones; David S. Weiss

doi:10.1371/journal.pone.0020609

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Open Access

Peer-reviewed

Research Article

TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

Crystal L. Jones,

Affiliations Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America
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David S. Weiss

* E-mail: david.weiss@emory.edu

Affiliations Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America, Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America
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TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

Crystal L. Jones,
David S. Weiss

Published: June 16, 2011
https://doi.org/10.1371/journal.pone.0020609

About the Authors

Crystal L. Jones

David S. Weiss

* E-mail: david.weiss@emory.edu

Affiliations Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America, Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CLJ DSW. Performed the experiments: CLJ DSW. Analyzed the data: CLJ DSW. Contributed reagents/materials/analysis tools: CLJ DSW. Wrote the paper: CLJ DSW.

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Inflammasomes
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Macrophages
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Cell death
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Immune receptor signaling
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Toll-like receptors
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Host cells
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Cytosol
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Intracellular pathogens
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