About the Authors

Dirk Bäumer

Affiliation MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

Sheena Lee

Affiliation MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

George Nicholson

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

Joanna L. Davies

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

Nicholas J. Parkinson

Affiliation MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

Lyndsay M. Murray

Affiliation Centre for Integrative Physiology and Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh Medical School, Edinburgh, United Kingdom

Thomas H. Gillingwater

Affiliation Centre for Integrative Physiology and Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh Medical School, Edinburgh, United Kingdom

Olaf Ansorge

Affiliation Department of Neuropathology, John Radcliffe Hospital, Oxford, United Kingdom

Kay E. Davies

Affiliation MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

Kevin Talbot

kevin.talbot@clneuro.ox.ac.uk

Affiliations MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DB KED KT. Performed the experiments: DB SL LMM THG OA. Analyzed the data: DB SL GN JLD OA. Contributed reagents/materials/analysis tools: SL GN NJP LMM THG. Wrote the paper: DB SL GN LMM THG KED KT.