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PLoS Computational Biology Issue Image | Vol. 2(10) October 2006

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Phylogenetic relationships in S. avermitilis

The modular architecture of type I polyketide synthases allows for truly natural biocombinatorics: creating new compounds very efficiently by recombination of gene segments. Shown here are the phylogenetic relationships of different domain types encoded in the genome of the actinobacterium Streptomyces avermitilis depicting an evolutionary history of extensive recombinational replacements (see Jenke-Kodama et al).

Image Credit: Illustration by Holger Jenke-Kodama

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Phylogenetic relationships in S. avermitilis

The modular architecture of type I polyketide synthases allows for truly natural biocombinatorics: creating new compounds very efficiently by recombination of gene segments. Shown here are the phylogenetic relationships of different domain types encoded in the genome of the actinobacterium Streptomyces avermitilis depicting an evolutionary history of extensive recombinational replacements (see Jenke-Kodama et al).

Image Credit: Illustration by Holger Jenke-Kodama

https://doi.org/10.1371/image.pcbi.v02.i10.g001