About the Authors

Nandor Gabor Than

nthan@med.wayne.edu

Affiliations First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary, Wayne State University, Detroit, Michigan, United States of America

Roberto Romero

Affiliation Wayne State University, Detroit, Michigan, United States of America

Hamutal Meiri

Affiliations Diagnostic Technologies Ltd., Yokneam, Israel, TeleMarpeh Ltd., Tel Aviv, Israel

Offer Erez

Affiliations Wayne State University, Detroit, Michigan, United States of America, Department of Obstetrics and Gynecology “B”, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel

Yi Xu

Affiliation Wayne State University, Detroit, Michigan, United States of America

Federica Tarquini

Affiliation Wayne State University, Detroit, Michigan, United States of America

Laszlo Barna

Affiliation Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary

Andras Szilagyi

Affiliation Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary

Ron Ackerman

Affiliation Diagnostic Technologies Ltd., Yokneam, Israel

Marei Sammar

Affiliations Diagnostic Technologies Ltd., Yokneam, Israel, Department of Biotechnology Engineering, ORT Braude College, Karmiel, Israel

Tibor Fule

Affiliation First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary

Katalin Karaszi

Affiliations First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary, First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary

Ilona Kovalszky

Affiliation First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary

Zhong Dong

Affiliation Wayne State University, Detroit, Michigan, United States of America

Chong Jai Kim

Affiliation Wayne State University, Detroit, Michigan, United States of America

Peter Zavodszky

Affiliation Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary

Zoltan Papp

Affiliation First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary

Ron Gonen

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, Bnai Zion Medical Center, Technion - Israel Institute of Technology, Haifa, Israel

Competing Interests

Dr. Hamutal Meiri was the former CEO and Director of Diagnostic Technologies Ltd (DTL) and had options for ordinary shares of the company, accounting for 3.5% of all issued shares on a fully diluted basis until the company went out of business and all options and shares were void. Dr. Sammar Marei and Dr. Hamutal Meiri were employees of DTL and their salaries were paid in part from the grants sponsoring this research. Dr. Ron Gonen obtained consulting fees at the time of patient enrollment to the clinical study but not during data analysis and manuscript writing. The authors have declared that no competing interests currently exist. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Designed and conceived the overall study and experiments: NGT. Designed and managed the clinical study and/or analyzed clinical data: NGT RR HM OE RG. Performed experiments: NGT YX FT RA MS TF KK. Analyzed and interpreted experimental data: NGT RR HM OE YX LB AS MS IK ZD CJK PZ ZP RG. Wrote or critically reviewed the manuscript: NGT RR HM OE YX FT LB AS RA MS TF KK IK ZD CJK PZ ZP RG.