Relating Neuronal Firing Patterns to Functional Differentiation of Cerebral Cortex
(A) The distribution of LvR determined across 2,000 ISI sequences for all 1,307 cortical neurons. (B) Top: Original and rescaled specimen spike sequences of representative neurons with an LvR of 0.5, 1.0, and 1.5 taken from data sets #2 (SMA), #10 (TE) and #19 (MT). Triangle and horizontal bars for the three original spike sequences indicate the onset of wrist movement and periods of visual stimulation, respectively. Dashed lines indicate the correspondence between the original and the rescaled fractions (10 ISIs) for which the time-scale is normalized to the average firing rate of that fraction. Bottom: Metric distributions for fractional sequences derived from neurons whose representative (mean) LvR values are within the range of ±0.05 around 0.5, 1.0, and 1.5 (blue, green and red bars in A, n = 92, 91 and 60). (C) LvR distributions for the 19 neuronal data sets (Table 1), shown in order of ascending mean LvR. The primary motor, higher-order motor, visual, and prefrontal areas are indicated as hexagons, pentagons, triangles, and squares, respectively.