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Glomeruli

Blockade of mTOR ameliorates IgA nephropathy by correcting CD89 and CD71 dysfunctions in humanized mice

Alexandra Cambier, Jennifer Da Silva, Julie Bex, Fanny Canesi, Lison Lachize Neanne, Aurélie Sannier, Hélène Mathieu, Erwan Boedec, Amandine Badie, Renato C. Monteiro

published 07 Oct 2025

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GlomSAM: Hybrid customized SAM for multi-glomerular detection and segmentation in immunofluorescence images

Shengyu Pan, Xuanli Tang, Bingxian Chen, Xiaobo Lai, Wei Jin

published 14 Apr 2025

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Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis

Liming Wang, Yuping Tang, Anne F. Buckley, Robert F. Spurney

published 10 Mar 2025

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Species-specific renal and liver responses during infection with food-borne trematodes Opisthorchis felineus, Opisthorchis viverrini, or Clonorchis sinensis

Oxana G. Zaparina, Yaroslav K. Kapushchak, Ekaterina A. Lishai, Sung-Jong Hong, Banchob Sripa, Maria Y. Pakharukova

published 05 Dec 2024

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Genetic deletion of calcium-independent phospholipase A₂γ protects mice from diabetic nephropathy

Andrey V. Cybulsky, Joan Papillon, Julie Guillemette, José R. Navarro-Betancourt, Hanan Elimam, I. George Fantus

published 31 Oct 2024

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Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis

Maroua Ferhat, Julia Mayer, Lyndon H. Costa, Maria Prendecki, Alejandro A. Puchol Tarazona, Alexander Schinagl, Randolf J. Kerschbaumer, Frederick W. K. Tam, Christine Landlinger, Michael Thiele

published 07 Oct 2024

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Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target

Lu Lin, Shulin Huang, Xin Lin, Xiaoling Liu, Xiangjin Xu, Chunmei Li, Pin Chen

published 27 Aug 2024

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Dach1 is essential for maintaining normal mature podocytes

Keiko Tanaka, Haruko Hayasaka, Taiji Matsusaka

published 28 May 2024

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Accelerated involution of germinal center in palatine tonsils in IgA nephropathy

Hiroyuki Ueda, Kensuke Joh, Yoshimi Ueda, Hirokazu Marumoto, Masahiro Okabe, Nao Isaka, Nobuo Tsuboi, Hiromi Kojima, Yoichi Miyazaki, Takashi Yokoo

published 06 May 2024

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Data retrieval from archival renal biopsies using nonlinear microscopy

Lucas C. Cahill, Tadayuki Yoshitake, Milan Rosen, Timothy D. Weber, James G. Fujimoto, Seymour Rosen

published 15 Mar 2024

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Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury

Anna Pezzotta, Luca Perico, Daniela Corna, Marina Morigi, Giuseppe Remuzzi, Ariela Benigni, Barbara Imberti

published 10 Oct 2023

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Neutrophil extracellular traps involved in the pathogenesis of IgA vasculitis: Confirmed in two IgAV rat models

Xiu-Qi Chen, Jia-Sen Zou, Li Tu, Xiang Yun, Yuan-Han Qin

published 21 Jul 2023

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Extracellular matrix and vascular dynamics in the kidney of a murine model for Marfan syndrome

Rodrigo Barbosa de Souza, Renan Barbosa Lemes, Orestes Foresto-Neto, Luara Lucena Cassiano, Dieter P. Reinhardt, Keith M. Meek, Ivan Hong Jun Koh, Philip N. Lewis, Lygia V. Pereira

published 09 May 2023

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