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Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

  • Clévio Nóbrega ,

    Contributed equally to this work with: Clévio Nóbrega, Isabel Nascimento-Ferreira

    Affiliation CNC - Center for Neurosciences & Cell Biology, University of Coimbra, Coimbra, Portugal

  • Isabel Nascimento-Ferreira ,

    Contributed equally to this work with: Clévio Nóbrega, Isabel Nascimento-Ferreira

    Affiliations CNC - Center for Neurosciences & Cell Biology, University of Coimbra, Coimbra, Portugal, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

  • Isabel Onofre,

    Affiliations CNC - Center for Neurosciences & Cell Biology, University of Coimbra, Coimbra, Portugal, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

  • David Albuquerque,

    Affiliation Faculty of Sciences and Technology, University of Coimbra, Coimbra, Portugal

  • Hirokazu Hirai,

    Affiliation Department of Neurophysiology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan

  • Nicole Déglon,

    Affiliation Lausanne University Hospital, Department of Clinical Neurosciences, Laboratory of Cellular and Molecular Neurotherapies, Lausanne, Switzerland

  • Luís Pereira de Almeida

    luispa@ci.uc.pt

    Affiliations CNC - Center for Neurosciences & Cell Biology, University of Coimbra, Coimbra, Portugal, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

  • Clévio Nóbrega, 
  • Isabel Nascimento-Ferreira, 
  • Isabel Onofre, 
  • David Albuquerque, 
  • Hirokazu Hirai, 
  • Nicole Déglon, 
  • Luís Pereira de Almeida
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