Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation

• Cong-Hui Yao,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Chemistry, Washington University, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

  http://orcid.org/0000-0003-3922-1874

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• Gao-Yuan Liu,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliations Department of Chemistry, Washington University, St. Louis, Missouri, United States of America, Department of Internal Medicine, Division of Bioorganic and Molecular Pharmacology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Rencheng Wang,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliations Department of Chemistry, Washington University, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Sung Ho Moon,

  Roles Project administration, Writing – review & editing

  Affiliations Department of Chemistry, Washington University, St. Louis, Missouri, United States of America, Department of Internal Medicine, Division of Bioorganic and Molecular Pharmacology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Richard W. Gross,

  Roles Conceptualization, Project administration, Writing – review & editing

  Affiliations Department of Chemistry, Washington University, St. Louis, Missouri, United States of America, Department of Internal Medicine, Division of Bioorganic and Molecular Pharmacology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Gary J. Patti

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gjpattij@wustl.edu

  Affiliations Department of Chemistry, Washington University, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

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