The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation

Pragyesh Dhungel; Shuai Cao; Zhilong Yang

doi:10.1371/journal.ppat.1006602

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Open Access

Peer-reviewed

Research Article

The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation

Pragyesh Dhungel,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Division of Biology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Shuai Cao,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Division of Biology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Zhilong Yang

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: zyang@ksu.edu

Affiliation Division of Biology, Kansas State University, Manhattan, Kansas, United States of America

http://orcid.org/0000-0001-8995-2654

⨯

The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation

Pragyesh Dhungel,
Shuai Cao,
Zhilong Yang

Published: August 30, 2017
https://doi.org/10.1371/journal.ppat.1006602

About the Authors

Pragyesh Dhungel

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Division of Biology, Kansas State University, Manhattan, Kansas, United States of America

Shuai Cao

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Division of Biology, Kansas State University, Manhattan, Kansas, United States of America

Zhilong Yang

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: zyang@ksu.edu

Affiliation Division of Biology, Kansas State University, Manhattan, Kansas, United States of America

http://orcid.org/0000-0001-8995-2654

Competing Interests

The authors have declared that no competing interests exist.

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Messenger RNA
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Protein translation
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Transfection
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Luciferase
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HeLa cells
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Internal ribosome entry site
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Small interfering RNA
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Viral gene expression
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