Evaluation of Exome Sequencing to Estimate Tumor Burden in Plasma

Daniel Klevebring; Mårten Neiman; Simon Sundling; Louise Eriksson; Eva Darai Ramqvist; Fuat Celebioglu; Kamila Czene; Per Hall; Lars Egevad; Henrik Grönberg; Johan Lindberg

doi:10.1371/journal.pone.0104417

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Open Access

Peer-reviewed

Research Article

Evaluation of Exome Sequencing to Estimate Tumor Burden in Plasma

Daniel Klevebring ,

Contributed equally to this work with: Daniel Klevebring, Mårten Neiman

Affiliation Department of Medical Epidemiology and Biostatistics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
⨯
Mårten Neiman ,

Contributed equally to this work with: Daniel Klevebring, Mårten Neiman

Affiliation Department of Medical Epidemiology and Biostatistics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
⨯
Simon Sundling,

Affiliation Department of Medical Epidemiology and Biostatistics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
⨯
Louise Eriksson,

Affiliation Department of Medical Epidemiology and Biostatistics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
⨯
Eva Darai Ramqvist,

Affiliation Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
⨯
Fuat Celebioglu,

Affiliation Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden
⨯
Kamila Czene,

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
⨯
Per Hall,

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
⨯
Lars Egevad,

Affiliation Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
⨯
Henrik Grönberg,

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
⨯
Johan Lindberg

* E-mail: johan.lindberg@ki.se

Affiliation Department of Medical Epidemiology and Biostatistics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
⨯

Evaluation of Exome Sequencing to Estimate Tumor Burden in Plasma

Daniel Klevebring,
Mårten Neiman,
Simon Sundling,
Louise Eriksson,
Eva Darai Ramqvist,
Fuat Celebioglu,
Kamila Czene,
Per Hall,
Lars Egevad,
Henrik Grönberg

Published: August 18, 2014
https://doi.org/10.1371/journal.pone.0104417

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Polymerase chain reaction
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Blood plasma
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Cancers and neoplasms
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Circulating tumor DNA
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